Background and Purpose. Assessment of the quality of randomized controlled trials (RCTs)
is common practice in systematic reviews. However, the reliability of data obtained with most …

Sorghum, an African grass related to sugar cane and maize, is grown for food, feed, fibre
and fuel. We present an initial analysis of the ∼730-megabase Sorghum bicolor (L.) Moench …

To correlate the variable clinical features of oestrogen-receptor-positive breast cancer with
somatic alterations, we studied pretreatment tumour biopsies accrued from patients in two …

Enhancer of zeste homolog 2 (EZH2) is a mammalian histone methyltransferase that contributes
to the epigenetic silencing of target genes and regulates the survival and metastasis of …

Most clinicians ask their patients to rate whether their health condition has improved or
deteriorated over time and then use this information to guide management decisions. Many …

We report the results of whole-genome and transcriptome sequencing of tumor and adjacent
normal tissue samples from 17 patients with non-small cell lung carcinoma (NSCLC). We …

Metastasis is a major contributor to cancer-associated deaths. It is characterized by a
multistep process that occurs through the acquisition of molecular and phenotypic changes …

Noncoding RNAs (ncRNAs) are emerging as key molecules in human cancer, with the
potential to serve as novel markers of disease and to reveal uncharacterized aspects of tumor …

Recurrent gene fusions, typically associated with haematological malignancies and rare bone
and soft-tissue tumours 1 , have recently been described in common solid tumours 2 , 3 , 4 …

Evidence-based practice involves the use of evidence from systematic reviews and randomised
controlled trials, but the extent of this evidence in physiotherapy has not previously been …