The developing heart is formed of two tissue layers separated by an extracellular matrix (ECM)
that provides chemical and physical signals to cardiac cells. While deposition of specific …

Aims Vertebrate heart development requires the complex morphogenesis of a linear tube to
form the mature organ, a process essential for correct cardiac form and function, requiring …

Developmental studies have shown that the evolutionarily conserved Wnt Planar Cell Polarity
(PCP) pathway is essential for the development of a diverse range of tissues and organs …

The establishment of the left-right axis is crucial for the placement, morphogenesis and
function of internal organs. Left-right specification is proposed to be dependent on cilia-driven …

During early vertebrate heart development, the heart transitions from a linear tube to a complex
asymmetric structure, a morphogenetic process that occurs simultaneously with growth of …

Localized mRNA translation is a widespread mechanism for targeting protein synthesis,
important for cell fate, motility and pathogenesis. In Drosophila, the spatiotemporal control of …

Egg activation is a universal process that includes a series of events to allow the fertilized
egg to complete meiosis and initiate embryonic development. One aspect of egg activation, …

During heart development, the embryonic ventricle becomes enveloped by the epicardium,
a layer of mesothelium which adheres to the outer apical surface of the heart. This is …

Aims: Bicuspid Aortic Valve (BAV) is the most common congenital heart defect, affecting at
least 2% of the population. The embryonic origins of BAV remain poorly understood, limiting …

Bicarbonate-based electrolytes are ubiquitous in aqueous electrochemical CO 2 reduction,
particularly in heterogenous catalysis, where they demonstrate improved catalytic …