Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density
lipoprotein cholesterol and triglycerides are among the most important risk factors for …

Population isolates such as those in Finland benefit genetic research because deleterious
alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor …

The second edition of this book has been written for the same audience as the first edition. It
is designed to be a" first port of call" for people wishing to study efficiency and productivity …

The Risk Assessment Work Group (Work Group) was composed of 11 members and 5 ex-officio
members, including internists, cardiologists, endocrinologists, and experts in …

Background High plasma HDL cholesterol is associated with reduced risk of myocardial
infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes are …

The American Heart Association (AHA) works with the Centers for Disease Control and
Prevention’s National Center for Health Statistics (CDC/NCHS); the National Heart, Lung, and …

Background— Visceral adipose tissue (VAT) compartments may confer increased metabolic
risk. The incremental utility of measuring both visceral and subcutaneous abdominal …

Emerging technologies allow the high-throughput profiling of metabolic status from a blood
specimen (metabolomics). We investigated whether metabolite profiles could predict the …

Blood pressure is a heritable trait 1 influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm …

Background Information is limited regarding the risk of cardiovascular disease in persons
with high-normal blood pressure (systolic pressure of 130 to 139 mm Hg, diastolic pressure of …