User profiles for Christopher J. Bott
Christopher BottPost-Doc University of Virginia Verified email at virginia.edu Cited by 427 |
Intermediate filaments in developing neurons: Beyond structure
CJ Bott, B Winckler - Cytoskeleton, 2020 - Wiley Online Library
Neuronal development relies on a highly choreographed progression of dynamic cellular
processes by which newborn neurons migrate, extend axons and dendrites, innervate their …
processes by which newborn neurons migrate, extend axons and dendrites, innervate their …
Loss of coiled-coil protein Cep55 impairs neural stem cell abscission and results in p53-dependent apoptosis in developing cortex
To build the brain, embryonic neural stem cells (NSCs) tightly regulate their cell divisions,
undergoing a polarized form of cytokinesis that is poorly understood. Cytokinetic abscission is …
undergoing a polarized form of cytokinesis that is poorly understood. Cytokinetic abscission is …
Nestin selectively facilitates the phosphorylation of the lissencephaly-linked protein doublecortin (DCX) by cdk5/p35 to regulate growth cone morphology and Sema3a …
Nestin, an intermediate filament protein widely used as a marker of neural progenitors, was
recently found to be expressed transiently in developing cortical neurons in culture and in …
recently found to be expressed transiently in developing cortical neurons in culture and in …
[HTML][HTML] Different Doublecortin (DCX) Patient Alleles Show Distinct Phenotypes in Cultured Neurons: EVIDENCE FOR DIVERGENT LOSS-OF-FUNCTION AND “OFF …
Doublecortin on the X-chromosome (DCX) is a neuronal microtubule-binding protein with a
multitude of roles in neurodevelopment. In humans, DCX is a major genetic locus for X-…
multitude of roles in neurodevelopment. In humans, DCX is a major genetic locus for X-…
Loss of coiled-coil protein Cep55 impairs abscission processes and results in p53-dependent apoptosis in developing cortex
To produce a brain of normal size and structure, embryonic neural stem cell (NSCs) must
tightly regulate their cell divisions. Cerebral cortex NSCs undergo a polarized form of …
tightly regulate their cell divisions. Cerebral cortex NSCs undergo a polarized form of …
[PDF][PDF] A novel signaling role for nestin in regulating growth cone morphology via the cdk5 substrate DCX
Bott et al. discovers a new mechanism by which the intermediate filament protein nestin
regulates growth cones: Nestin complexes with the lissencephaly-linked protein DCX and …
regulates growth cones: Nestin complexes with the lissencephaly-linked protein DCX and …
Nestin in immature embryonic neurons regulates axon growth cone morphology and Semaphorin3a sensitivity
Correct wiring in the neocortex requires that responses to an individual guidance cue vary
among neurons in the same location, and within the same neuron over time. Nestin is an …
among neurons in the same location, and within the same neuron over time. Nestin is an …
Influence of river level on temperature and hydraulic gradients in chum and fall Chinook salmon spawning areas downstream of Bonneville Dam, Columbia River
…, CJ Murray, KE McGrath, YJ Bott… - … American Journal of …, 2008 - Taylor & Francis
Chum salmon Oncorhynchus keta and fall Chinook salmon O. tshawytscha segregate spatially
during spawning in the Ives Island side channel of the lower Columbia River downstream …
during spawning in the Ives Island side channel of the lower Columbia River downstream …
[PDF][PDF] Chan Choo Yap, Laura Digilio, Lloyd McMahon, Matylda Roszkowska1, Christopher J. Bott
K Kruczek, B Winckler - 2016 - researchgate.net
DCX (doublecortin on the X-chromosome) is a neuronal microtubule-binding protein with a
multitude of roles in neurodevelopment. In humans, DCX is a major genetic locus for X-linked …
multitude of roles in neurodevelopment. In humans, DCX is a major genetic locus for X-linked …
Establishing a geochemical heterogeneity model for a contaminated vadose zone—Aquifer system
…, JM Zachara, JP McKinley, A Ward, YJ Bott… - Journal of contaminant …, 2013 - Elsevier
A large set of sediment samples from a 1600 m 2 experimental plot within a 2.2 km 2
vadose zone and groundwater uranium (VI) plume was subject to physical, chemical, and …
vadose zone and groundwater uranium (VI) plume was subject to physical, chemical, and …