The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α helices: crystal structure of the protein-DNA complex
The yeast transcriptional activator GCN4 is 1 of over 30 identified eukaryotic proteins
containing the basic region leucine zipper (bZIP) DNA-binding motif. We have determined the …
containing the basic region leucine zipper (bZIP) DNA-binding motif. We have determined the …
Amino-acid sequence of a Ca2+ + Mg2+ -dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence
DH MacLennan, CJ Brandl, B Korczak, NM Green - Nature, 1985 - nature.com
We have cloned and sequenced complementary DNA encoding a Ca 2+ -ATPase of rabbit
muscle sarcoplasmic reticulum. We propose a model of the protein which has 3 cytoplasmic …
muscle sarcoplasmic reticulum. We propose a model of the protein which has 3 cytoplasmic …
Two Ca2+ ATPase genes: homologies and mechanistic implications of deduced amino acid sequences
CJ Brandl, NM Green, B Korczak, DH MacLennan - Cell, 1986 - cell.com
Rabbit genomic DNA contains two genes that encode Ca*+ ATPases of fast twitch and of
slow twitch (and cardiac) sarcoplasmic reticulum, respectively. The deduced amino acid …
slow twitch (and cardiac) sarcoplasmic reticulum, respectively. The deduced amino acid …
[HTML][HTML] NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM‐related cofactor Tra1p
Post‐translational acetylation of histone H4 N‐terminal tail in chromatin has been associated
with several nuclear processes including transcription. We report the purification and …
with several nuclear processes including transcription. We report the purification and …
Defining the sequence specificity of DNA-binding proteins by selecting binding sites from random-sequence oligonucleotides: analysis of yeast GCN4 protein
We describe a new method for accurately defining the sequence recognition properties of
DNA-binding proteins by selecting high-affinity binding sites from random-sequence DNA. The …
DNA-binding proteins by selecting high-affinity binding sites from random-sequence DNA. The …
Hypothesis about the function of membrane-buried proline residues in transport proteins.
In a survey of the bilayer-spanning regions of integral membrane proteins, membrane-buried
proline residues were found in nearly all transport proteins examined, whereas membrane-…
proline residues were found in nearly all transport proteins examined, whereas membrane-…
Regulation of myocardial Ca2+-ATPase and phospholamban mRNA expression in response to pressure overload and thyroid hormone.
…, A Zarain-Herzberg, CJ Brandl, J Fujii… - Proceedings of the …, 1989 - National Acad Sciences
The sarcoplasmic reticulum (SR) and the contractile protein myosin play an important role in
myocardial performance. Both of these systems exhibit plasticity--ie, quantitative and/or …
myocardial performance. Both of these systems exhibit plasticity--ie, quantitative and/or …
[HTML][HTML] Tra1p is a component of the yeast Ada· Spt transcriptional regulatory complexes
The yeast Ada and TBP class of Spt proteins interact in multiple complexes that are required
for transcriptional regulation. We have identified Tra1p as a component of these complexes …
for transcriptional regulation. We have identified Tra1p as a component of these complexes …
Transfer RNAs: diversity in form and function
As the adaptor that decodes mRNA sequence into protein, the basic aspects of tRNA structure
and function are central to all studies of biology. Yet the complexities of their properties …
and function are central to all studies of biology. Yet the complexities of their properties …
[HTML][HTML] Pathways to disease from natural variations in human cytoplasmic tRNAs
Perfectly accurate translation of mRNA into protein is not a prerequisite for life. Resulting
from errors in protein synthesis, mistranslation occurs in all cells, including human cells. The …
from errors in protein synthesis, mistranslation occurs in all cells, including human cells. The …