[HTML][HTML] Rotavirus and severe childhood diarrhea
UD Parashar, CJ Gibson, JS Bresee… - Emerging infectious …, 2006 - ncbi.nlm.nih.gov
Studies published between 1986 and 1999 indicated that rotavirus causes≈ 22%(range 17%–28%)
of childhood diarrhea hospitalizations. From 2000 to 2004, this proportion …
of childhood diarrhea hospitalizations. From 2000 to 2004, this proportion …
[HTML][HTML] Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease
…, P Natarajan, AJ Silver, CJ Gibson… - … England Journal of …, 2017 - Mass Medical Soc
Background Clonal hematopoiesis of indeterminate potential (CHIP), which is defined as
the presence of an expanded somatic blood-cell clone in persons without other hematologic …
the presence of an expanded somatic blood-cell clone in persons without other hematologic …
Cancer therapy shapes the fitness landscape of clonal hematopoiesis
…, B Spitzer, S Mantha, J Fagin, L Boucai, CJ Gibson… - Nature …, 2020 - nature.com
Acquired mutations are pervasive across normal tissues. However, understanding of the
processes that drive transformation of certain clones to cancer is limited. Here we study this …
processes that drive transformation of certain clones to cancer is limited. Here we study this …
Inherited causes of clonal haematopoiesis in 97,691 whole genomes
Age is the dominant risk factor for most chronic human diseases, but the mechanisms
through which ageing confers this risk are largely unknown 1 . The age-related acquisition of …
through which ageing confers this risk are largely unknown 1 . The age-related acquisition of …
The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia
AS Sperling, CJ Gibson, BL Ebert - Nature Reviews Cancer, 2017 - nature.com
Myelodysplastic syndrome (MDS) is a clonal disease that arises from the expansion of
mutated haematopoietic stem cells. In a spectrum of myeloid disorders ranging from clonal …
mutated haematopoietic stem cells. In a spectrum of myeloid disorders ranging from clonal …
Distinction of lymphoid and myeloid clonal hematopoiesis
Clonal hematopoiesis (CH) results from somatic genomic alterations that drive clonal
expansion of blood cells. Somatic gene mutations associated with hematologic malignancies …
expansion of blood cells. Somatic gene mutations associated with hematologic malignancies …
[HTML][HTML] Clonal hematopoiesis associated with adverse outcomes after autologous stem-cell transplantation for lymphoma
CJ Gibson, RC Lindsley, V Tchekmedyian… - Journal of Clinical …, 2017 - ncbi.nlm.nih.gov
Purpose Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition
characterized by somatic mutations in the blood of otherwise healthy adults. We …
characterized by somatic mutations in the blood of otherwise healthy adults. We …
A disease risk index for patients undergoing allogeneic stem cell transplantation
…, CJ Gibson, C Cutler, VT Ho, J Koreth… - Blood, The Journal …, 2012 - ashpublications.org
The outcome of allogeneic HSCT varies considerably by the disease and remission status
at the time of transplantation. Any retrospective or prospective HSCT study that enrolls …
at the time of transplantation. Any retrospective or prospective HSCT study that enrolls …
Prediction of risk for myeloid malignancy in clonal hematopoiesis
Background Clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia
of undetermined significance (CCUS) are defined by somatic mutations in genes associated …
of undetermined significance (CCUS) are defined by somatic mutations in genes associated …
Association of clonal hematopoiesis with chronic obstructive pulmonary disease
…, MC Honigberg, AS Sperling, CJ Gibson… - Blood, The Journal …, 2022 - ashpublications.org
Chronic obstructive pulmonary disease (COPD) is associated with age and smoking, but
other determinants of the disease are incompletely understood. Clonal hematopoiesis of …
other determinants of the disease are incompletely understood. Clonal hematopoiesis of …