Purpose of Review Although a fine-grained understanding of the neurobiology of posttraumatic
stress disorder (PTSD) is yet to be elucidated, the last two decades have seen a rapid …

Posttraumatic stress disorder (PTSD) is a chronic and debilitating psychiatric disorder afflicting
millions of individuals across the world. While the availability of robust pharmacologic …

The ability of ketamine administration to activate prefrontal glutamate neurotransmission is
thought to be a key mechanism contributing to its transient psychotomimetic effects and its …

Disruption in the default mode network (DMN) has been implicated in numerous neuropsychiatric
disorders, including posttraumatic stress disorder (PTSD). However, studies have …

New approaches to the neurobiology of posttraumatic stress disorder (PTSD) are needed to
address the reported crisis in PTSD drug development. These new approaches may require …

Background Prefrontal global brain connectivity with global signal regression (GBCr) was
proposed as a robust biomarker of depression and was associated with ketamine’s …

We investigated the extent of cortical thinning in US Veterans exposed to combat who
varied in the severity of their posttraumatic stress disorder (PTSD) symptoms. In addition, we …

A growing number of studies have examined alterations in white matter organization in people
with posttraumatic stress disorder (PTSD) using diffusion MRI (dMRI), but the results have …

Background Posttraumatic stress disorder (PTSD) is associated with markers of accelerated
aging. Estimates of brain age, compared to chronological age, may clarify the effects of …

Background The hippocampus and amygdala have been repeatedly implicated in the
psychopathology of posttraumatic stress disorder (PTSD). While numerous structural …