Drosophila Fascin is a novel downstream target of prostaglandin signaling during actin remodeling
CM Groen, AJ Spracklen, TN Fagan… - Molecular biology of the …, 2012 - Am Soc Cell Biol
Although prostaglandins (PGs)—lipid signals produced downstream of cyclooxygenase (COX)
enzymes—regulate actin cytoskeletal dynamics, their mechanisms of action are unknown…
enzymes—regulate actin cytoskeletal dynamics, their mechanisms of action are unknown…
Genetic reduction of mitochondria complex I subunits is protective against cisplatin-induced neurotoxicity in Drosophila
CM Groen, JL Podratz, J Pathoulas, N Staff… - Journal of …, 2022 - Soc Neuroscience
Chemotherapy-induced peripheral neuropathy (CIPN) is a prevalent side effect of widely
used platinum-based anticancer agents. There are few predictable risk factors with which to …
used platinum-based anticancer agents. There are few predictable risk factors with which to …
Fascin regulates nuclear actin during Drosophila oogenesis
DJ Kelpsch, CM Groen, TN Fagan… - Molecular biology of …, 2016 - Am Soc Cell Biol
Drosophila oogenesis provides a developmental system with which to study nuclear actin.
During Stages 5–9, nuclear actin levels are high in the oocyte and exhibit variation within the …
During Stages 5–9, nuclear actin levels are high in the oocyte and exhibit variation within the …
The evolving regulatory landscape in regenerative medicine
DJ Beetler, DN Di Florio, EW Law, CM Groen… - Molecular aspects of …, 2023 - Elsevier
Regenerative medicine as a field has emerged as a new component of modern medicine
and medical research that encompasses a wide range of products including cellular and …
and medical research that encompasses a wide range of products including cellular and …
Prostaglandins regulate nuclear localization of Fascin and its function in nucleolar architecture
Fascin, a highly conserved actin-bundling protein, localizes and functions at new cellular
sites in both Drosophila and multiple mammalian cell types. During Drosophila follicle …
sites in both Drosophila and multiple mammalian cell types. During Drosophila follicle …
Pharmaco-Genetic Screen To Uncover Actin Regulators Targeted by Prostaglandins During Drosophila Oogenesis
AJ Spracklen, MC Lamb, CM Groen… - G3: Genes, Genomes …, 2019 - academic.oup.com
Prostaglandins (PGs) are lipid signaling molecules with numerous physiologic functions,
including pain/inflammation, fertility, and cancer. PGs are produced downstream of …
including pain/inflammation, fertility, and cancer. PGs are produced downstream of …
Drosophila strain specific response to cisplatin neurotoxicity
CM Groen, JL Podratz, K Treb, AJ Windebank - Fly, 2018 - Taylor & Francis
Drosophila melanogaster has recently been developed as a simple, in vivo, genetic model
of chemotherapy-induced peripheral neuropathy. Flies treated with the chemotherapy agent …
of chemotherapy-induced peripheral neuropathy. Flies treated with the chemotherapy agent …
Mini-course-based undergraduate research experience
…, AK Allen, AJ Spracklen, CM Groen… - Journal of College …, 2019 - JSTOR
Undergraduate research experiences (UREs) increase interest in STEM (science, technology,
engineering, and mathematics) research and careers. UREs are utilized as recruitment …
engineering, and mathematics) research and careers. UREs are utilized as recruitment …
Promoting international collaboration and creativity in doctoral students
CM Groen, C McGrath, KA Campbell, C Götherström… - ELife, 2017 - elifesciences.org
… CHRISTOPHER M GROEN, CORMAC MCGRATH, KATHERINE A CAMPBELL, CECILIA
GO THERSTRO M, ANTHONY J WINDEBANK AND NATALIA LANDA ZURI* … Copyright …
GO THERSTRO M, ANTHONY J WINDEBANK AND NATALIA LANDA ZURI* … Copyright …
Visualization of Actin Cytoskeletal Dynamics in Fixed and Live Drosophila Egg Chambers
CM Groen, TL Tootle - Drosophila Oogenesis: Methods and Protocols, 2015 - Springer
Visualization of actin cytoskeletal dynamics is critical for understanding the spatial and
temporal regulation of actin remodeling. Drosophila oogenesis provides an excellent model …
temporal regulation of actin remodeling. Drosophila oogenesis provides an excellent model …