Heme overdrive rewires pan-cancer cell metabolism

SR Adapa, GA Hunter, NE Amin, C Marinescu… - bioRxiv, 2022 - biorxiv.org
All cancers reprogram their metabolism. In this study, we report that all cancer cells employ
imbalanced and dynamic heme metabolic pathways essential for their oncogenic growth and …

Bait-and-Kill: Targeting a Novel Heme Biochemical Pathway in Hundreds of Cancers

CG Marinescu - 2021 - search.proquest.com
Cancer cells are characterized by their ability to grow and proliferate in rates that far exceed
normal cells by modifying their iron/heme metabolisms to levels higher than normal. This …

Pulmonary apical cap as a potential risk factor for pleuroparenchymal fibroelastosis

DC Marinescu, J English, T Sedlic, A Kliber… - Chest, 2021 - Elsevier
Pleuroparenchymal fibroelastosis (PPFE) is a progressive and frequently fatal interstitial
lung disease that involves the upper lobes. Although its cause remains unknown, the …

Coronary microvascular dysfunction, microvascular angina, and treatment strategies

MA Marinescu, AI Löffler, M Ouellette, L Smith… - JACC: Cardiovascular …, 2015 - jacc.org
Angina without coronary artery disease (CAD) has substantial morbidity and is present in 10%
to 30% of patients undergoing angiography. Coronary microvascular dysfunction (CMD) …

Mismatch unemployment and the geography of job search

I Marinescu, R Rathelot - American Economic Journal …, 2018 - aeaweb.org
Could we significantly reduce US unemployment by helping job seekers move closer to jobs?
Using data from the leading employment board CareerBuilder.com, we show that, indeed, …

Integration and application of clinical practice guidelines for the diagnosis of idiopathic pulmonary fibrosis and fibrotic hypersensitivity pneumonitis

DC Marinescu, G Raghu, M Remy-Jardin, WD Travis… - Chest, 2022 - Elsevier
Recent clinical practice guidelines have addressed the diagnosis of idiopathic pulmonary
fibrosis (IPF) and fibrotic hypersensitivity pneumonitis (fHP). These disease-specific guidelines …

Opening the black box of the matching function: The power of words

I Marinescu, R Wolthoff - Journal of Labor Economics, 2020 - journals.uchicago.edu
On the leading job board CareerBuilder.com , high-wage job postings unexpectedly attract
fewer applicants, and this is the case even within a detailed occupation. Viewed through the …

[BOOK][B] EJB design patterns

F Marinescu - 2002 - box.cs.istu.ru
… “Floyd Marinescu has done a great job of documenting and organizing a cornucopia of EJB
… This book is dedicated to my little sister Jacqueline Marinescu. Let this book stand as proof …

[HTML][HTML] Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

AL Young, RV Marinescu, NP Oxtoby… - Nature …, 2018 - nature.com
The heterogeneity of neurodegenerative diseases is a key confound to disease understanding
and treatment development, as study cohorts typically include multiple phenotypes on …

Integration and application of radiologic patterns from clinical practice guidelines on idiopathic pulmonary fibrosis and fibrotic hypersensitivity pneumonitis

DC Marinescu, CJ Hague, NL Muller, D Murphy… - Chest, 2023 - Elsevier
Background Clinical practice guidelines separately describe radiologic patterns of usual
interstitial pneumonia (UIP) and fibrotic hypersensitivity pneumonitis (fHP), without direction on …