User profiles for Christopher Moxon
 | Christopher Alan MoxonSenior Clinical Lecturer, Wellcome Centre for Molecular Parasitology, University of Glasgow Verified email at glasgow.ac.uk Cited by 1475 |
Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African children
Cerebral malaria (CM) is a major cause of mortality in African children and the mechanisms
underlying its development, namely how malaria-infected erythrocytes (IEs) cause disease …
underlying its development, namely how malaria-infected erythrocytes (IEs) cause disease …
New insights into malaria pathogenesis
Malaria remains a major public health threat in tropical and subtropical regions across the
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …
Neutrophil extracellular traps drive inflammatory pathogenesis in malaria
…, A Georgiadou, F Apel, U Abu-Abed, CA Moxon… - Science …, 2019 - science.org
Neutrophils are essential innate immune cells that extrude chromatin in the form of
neutrophil extracellular traps (NETs) when they die. This form of cell death has potent …
neutrophil extracellular traps (NETs) when they die. This form of cell death has potent …
Cerebral malaria is associated with differential cytoadherence to brain endothelial cells
Sequestration of Plasmodium falciparum‐infected erythrocytes ( IE ) within the brain
microvasculature is a hallmark of cerebral malaria ( CM ). Using a microchannel flow adhesion …
microvasculature is a hallmark of cerebral malaria ( CM ). Using a microchannel flow adhesion …
Malaria: modification of the red blood cell and consequences in the human host
Residence in the human erythrocyte is essential for the lifecycle of all Plasmodium that infect
man. It is also the phase of the life cycle that causes disease. Although the red blood cell (…
man. It is also the phase of the life cycle that causes disease. Although the red blood cell (…
[HTML][HTML] Dysregulation of coagulation in cerebral malaria
Cerebral malaria (CM) is a life-threatening complication of Plasmodium falciparum infection
and represents a major cause of morbidity and mortality worldwide. The nature of the …
and represents a major cause of morbidity and mortality worldwide. The nature of the …
[HTML][HTML] Effects of saline or albumin fluid bolus in resuscitation: evidence from re-analysis of the FEAST trial
Background Fluid resuscitation is the recommended management of shock, but increased
mortality in febrile African children in the FEAST trial. We hypothesised that fluid bolus-…
mortality in febrile African children in the FEAST trial. We hypothesised that fluid bolus-…
Beta-lactamases in Enterobacteriaceae infections in children
CA Moxon, S Paulus - Journal of infection, 2016 - Elsevier
… Author links open overlay panelChristopher Alan Moxon a b c , Stéphane Paulus a b …
Christopher Moxon and Stéphane Paulus have no conflicts of interest to declare. …
Christopher Moxon and Stéphane Paulus have no conflicts of interest to declare. …
Host cell maturation modulates parasite invasion and sexual differentiation in Plasmodium berghei
Malaria remains a global health problem causing more than 400,000 deaths annually.
Plasmodium parasites, the causative agents of malaria, replicate asexually in red blood cells (…
Plasmodium parasites, the causative agents of malaria, replicate asexually in red blood cells (…
Vascular endothelial cells cultured from patients with cerebral or uncomplicated malaria exhibit differential reactivity to TNF
Plasmodium falciparum malaria is a major cause of morbidity and mortality in African
children, and factors that determine the development of uncomplicated (UM) versus cerebral …
children, and factors that determine the development of uncomplicated (UM) versus cerebral …