User profiles for Christopher Naranjo
Christopher NaranjoMD Candidate, Vanderbilt University School of Medicine Verified email at vanderbilt.edu Cited by 78 |
[HTML][HTML] Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development
Cerebrospinal fluid (CSF) provides vital support for the brain. Abnormal CSF accumulation,
such as hydrocephalus, can negatively affect perinatal neurodevelopment. The mechanisms …
such as hydrocephalus, can negatively affect perinatal neurodevelopment. The mechanisms …
SARS-CoV-2 receptor binding domain displayed on HBsAg virus–like particles elicits protective immunity in macaques
…, F Nampanya, S Patel, L Bowman, CA Naranjo… - Science …, 2022 - science.org
Authorized vaccines against SARS-CoV-2 remain less available in low- and middle-income
countries due to insufficient supply, high costs, and storage requirements. Global immunity …
countries due to insufficient supply, high costs, and storage requirements. Global immunity …
Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice
…, M Silva, RS Johnston, CA Naranjo… - Proceedings of the …, 2021 - National Acad Sciences
Global containment of COVID-19 still requires accessible and affordable vaccines for low-
and middle-income countries (LMICs). Recently approved vaccines provide needed …
and middle-income countries (LMICs). Recently approved vaccines provide needed …
Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2
There is a need for additional rapidly scalable, low-cost vaccines against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) to achieve global vaccination. Aluminum …
respiratory syndrome coronavirus 2 (SARS-CoV-2) to achieve global vaccination. Aluminum …
Scalable, methanol‐free manufacturing of the SARS‐CoV‐2 receptor‐binding domain in engineered Komagataella phaffii
…, SA Rodriguez‐Aponte, CA Naranjo… - Biotechnology and …, 2022 - Wiley Online Library
Prevention of COVID‐19 on a global scale will require the continued development of high‐volume,
low‐cost platforms for the manufacturing of vaccines to supply ongoing demand. …
low‐cost platforms for the manufacturing of vaccines to supply ongoing demand. …
[HTML][HTML] Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters
…, KA Rodrigues, M Silva, RS Johnston, CA Naranjo… - BioRxiv, 2021 - ncbi.nlm.nih.gov
Global containment of COVID-19 still requires accessible and affordable vaccines for low-and
middle-income countries (LMICs). 1 Recently approved vaccines provide needed …
middle-income countries (LMICs). 1 Recently approved vaccines provide needed …
Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG …
…, NC Dalvie, CA Naranjo… - Human Vaccines & …, 2022 - Taylor & Francis
Low-cost, refrigerator-stable COVID-19 vaccines will facilitate global access and improve
vaccine coverage in low- and middle-income countries. To this end, subunit-based approaches …
vaccine coverage in low- and middle-income countries. To this end, subunit-based approaches …
[HTML][HTML] A modular protein subunit vaccine candidate produced in yeast confers protection against SARS-CoV-2 in non-human primates
…, F Nampanya, S Patel, L Bowman, CA Naranjo… - bioRxiv, 2021 - ncbi.nlm.nih.gov
Vaccines against SARS-CoV-2 have been distributed at massive scale in developed countries,
and have been effective at preventing COVID-19. Access to vaccines is limited, however, …
and have been effective at preventing COVID-19. Access to vaccines is limited, however, …
[HTML][HTML] Association of hypothermia with increased mortality rate in SARS-CoV-2 infection
…, RG Santos, R Zeidan, AP Gastesi, CD Naranjo - International Journal of …, 2021 - Elsevier
Objective Patients were observed to have variable temperatures. The objective of this study
was to identify whether hypothermia in a patient infected with SARS-CoV-2 was associated …
was to identify whether hypothermia in a patient infected with SARS-CoV-2 was associated …
An intravenous DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies
…, Z An, S Patel, S Rodriguez-Aponte, CA Naranjo… - bioRxiv, 2023 - biorxiv.org
Blood-based, or “liquid,” biopsies enable minimally invasive diagnostics but have limits on
sensitivity due to scarce cell-free DNA (cfDNA). Improvements to sensitivity have primarily …
sensitivity due to scarce cell-free DNA (cfDNA). Improvements to sensitivity have primarily …