Multiplex digital spatial profiling of proteins and RNA in fixed tissue

CR Merritt, GT Ong, SE Church, K Barker… - Nature …, 2020 - nature.com
Digital Spatial Profiling (DSP) is a method for highly multiplex spatial profiling of proteins or
RNAs suitable for use on formalin-fixed, paraffin-embedded (FFPE) samples. The approach …

High-plex predictive marker discovery for melanoma immunotherapy–treated patients using digital spatial profiling

MI Toki, CR Merritt, PF Wong, JW Smithy… - Clinical Cancer …, 2019 - AACR
Purpose: Protein expression in formalin-fixed, paraffin-embedded tissue is routinely measured
by IHC or quantitative fluorescence (QIF) on a handful of markers on a single section. …

GeoMx™ RNA assay: high multiplex, digital, spatial analysis of RNA in FFPE tissue

…, SE Lingle, K Sorg, JM Beechem, CR Merritt - In Situ Hybridization …, 2020 - Springer
RNA in situ hybridization (ISH) is a widely used technique for the localization of mRNA in
tissues. Limitations to traditional ISH include the number of targets that can be analyzed …

The risk of exposure to diagnostic ultrasound in postnatal subjects: thermal effects

…, GR Harris, BA Herman, CR Merritt… - … of Ultrasound in …, 2008 - Wiley Online Library
This review evaluates the thermal mechanism for ultrasound‐induced biological effects in
postnatal subjects. The focus is the evaluation of damage versus temperature increase. A view …

Bulk synthesis of graphene-like materials possessing turbostratic graphite and graphene nanodomains via combustion of magnesium in carbon dioxide

TH Kim, CR Merritt, C Ducati, AD Bond, N Bampos… - Carbon, 2019 - Elsevier
This study reports a gram scale synthesis of a turbostratically aligned carbon material containing
regions of graphite and few-layer graphene located in carbon-only nanodomains. The …

Hydrogen adsorption characteristics of magnesium combustion derived graphene at 77 and 293 K

BV Cunning, DS Pyle, CR Merritt, CL Brown… - International Journal of …, 2014 - Elsevier
Bulk graphene was prepared by the method of magnesium combustion in a CO 2 atmosphere,
producing large quantities of material which had a different morphology and importantly, …

Role of oxygen-containing functional groups in forest fire-generated and pyrolytic chars for immobilization of copper and nickel

M Esfandbod, CR Merritt, MR Rashti, B Singh… - Environmental …, 2017 - Elsevier
Char as a carbon-rich material, can be produced under pyrolytic conditions, wildfires or
prescribed burn offs for fire management. The objective of this study was to elucidate …

Long-term results of sleeve lobectomy in the management of non–small cell lung carcinoma and low-grade neoplasms

RE Merritt, DJ Mathisen, JC Wain, HA Gaissert… - The Annals of thoracic …, 2009 - Elsevier
BACKGROUND: The objective of this study was to evaluate the operative mortality, morbidity,
and long-term survival of sleeve lobectomy for non–small cell lung cancer and low-grade …

A Video-Based Procedure-Specific Competency Assessment Tool for Minimally Invasive Esophagectomy

…, AH Hölscher, S Law, MDP Luyer, RE Merritt… - Jama …, 2024 - jamanetwork.com
Importance Minimally invasive esophagectomy (MIE) is a complex procedure with substantial
learning curves. In other complex minimally invasive procedures, suboptimal surgical …

[BOOK][B] 3'untranslated regions are the primary regulators of gene expression in the Caenorhabditis elegans germline

CR Merritt - 2010 - search.proquest.com
How genes are regulated to produce the correct assortment of proteins for every cell type is
a fundamental question in biology. For many genes, regulation begins at the DNA level …