… TRH Davenport and Christopher Saunders … Discerning readers should not be surprised
to see the name of Christopher Saunders on the title page of this edition. After studying at …

Methods for automated prediction of deleterious protein mutations have utilized both structural
and evolutionary information but the relative contribution of these two factors remains …

The sperm-specific phospholipase C-ζ (PLCζ) elicits fertilization-like Ca 2+ oscillations and
activation of embryo development when microinjected into mammalian eggs (Saunders, CM, …

Motivation: Whole genome and exome sequencing of matched tumor–normal sample pairs
is becoming routine in cancer research. The consequent increased demand for somatic …

We describe Manta, a method to discover structural variants and indels from next generation
sequencing data. Manta is optimized for rapid germline and somatic analysis, calling …

Upon fertilisation by sperm, mammalian eggs are activated by a series of intracellular Ca 2+
oscillations that are essential for embryo development. The mechanism by which sperm …

We describe Strelka2 ( https://github.com/Illumina/strelka ), an open-source small-variant-calling
method for research and clinical germline and somatic sequencing applications. …

Photovoltaic (PV) systems integration is increasingly being used to reduce fuel consumption
in diesel-based remote microgrids. However, uncertainty and low correlation of PV power …

An ultrafast DNA sequence aligner (Isaac Genome Alignment Software) that takes advantage
of high-memory hardware (>48 GB) and variant caller (Isaac Variant Caller) have been …

A novel procedure for estimating the total inertia of the Great Britain (GB) power system is
presented. Following an instantaneous in-feed loss, regional variations in the estimate of …