Background Cytidine deamination that is guided by clustered regularly interspaced short
palindromic repeats (CRISPR) can mediate a highly precise conversion of one nucleotide into …

We discuss the integration of contextual information with team-based access control. The
TMAC model was formulated by Thomas in [1] to provide access control for collaborative …

Genome editing of allogeneic T cells can provide “off-the-shelf” alternatives to autologous
chimeric antigen receptor (CAR) T cell therapies. Disruption of T cell receptor α chain (TRAC) …

Invertebrates constitute the majority of animal species and are critical for ecosystem
functioning and services. Nonetheless, global invertebrate biodiversity patterns and their …

Collaborative filtering is one of the most used approaches for providing recommendations in
various online environments. Even though collaborative recommendation methods have …

Purpose – This study aims to identify the similarities and differences between the perspectives
of providers and customers regarding the important dimensions and attributes of e‐…

Gene editing can be used to overcome allo-recognition, which otherwise limits allogeneic T
cell therapies. Initial proof-of-concept applications have included generation of such "…

Targeting T cell malignancies using chimeric antigen receptor (CAR) T cells is hindered by ‘T
v T’ fratricide against shared antigens such as CD3 and CD7. Base editing offers the …

T cells engineered to express chimeric antigen receptors (CARs) against B cell antigens are
being investigated as cellular immunotherapies. Similar approaches designed to target T …

Collaborative recommender systems offer a solution to the information overload problem
found in online environments such as e-commerce. The use of collaborative filtering, the most …