[HTML][HTML] What every reader should know about studies using electronic health record data but may be afraid to ask
Coincident with the tsunami of COVID-19–related publications, there has been a surge of
studies using real-world data, including those obtained from the electronic health record (EHR)…
studies using real-world data, including those obtained from the electronic health record (EHR)…
[HTML][HTML] Empirical comparison of publication bias tests in meta-analysis
Background Decision makers rely on meta-analytic estimates to trade off benefits and harms.
Publication bias impairs the validity and generalizability of such estimates. The …
Publication bias impairs the validity and generalizability of such estimates. The …
Structure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex
Classically, G-protein-coupled receptors (GPCRs) are thought to activate G protein from the
plasma membrane and are subsequently desensitized by β-arrestin (β-arr). However, some …
plasma membrane and are subsequently desensitized by β-arrestin (β-arr). However, some …
Architecture of the human GATOR1 and GATOR1–Rag GTPases complexes
…, L Chantranupong, A Bomaliyamu, A Choe, C Hong… - Nature, 2018 - nature.com
Nutrients, such as amino acids and glucose, signal through the Rag GTPases to activate
mTORC1. The GATOR1 protein complex—comprising DEPDC5, NPRL2 and NPRL3—…
mTORC1. The GATOR1 protein complex—comprising DEPDC5, NPRL2 and NPRL3—…
[HTML][HTML] Long-term kidney function recovery and mortality after COVID-19-associated acute kidney injury: an international multi-centre observational cohort study
Background While acute kidney injury (AKI) is a common complication in COVID-19, data
on post-AKI kidney function recovery and the clinical factors associated with poor kidney …
on post-AKI kidney function recovery and the clinical factors associated with poor kidney …
Testing small study effects in multivariate meta-analysis
Small study effects occur when smaller studies show different, often larger, treatment effects
than large ones, which may threaten the validity of systematic reviews and meta-analyses. …
than large ones, which may threaten the validity of systematic reviews and meta-analyses. …
[HTML][HTML] Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation
Narcolepsy type 1 (NT1) is a chronic neurological disorder that impairs the brain’s ability to
control sleep-wake cycles. Current therapies are limited to the management of symptoms …
control sleep-wake cycles. Current therapies are limited to the management of symptoms …
Federated and distributed learning applications for electronic health records and structured medical data: a scoping review
Objectives Federated learning (FL) has gained popularity in clinical research in recent years
to facilitate privacy-preserving collaboration. Structured data, one of the most prevalent …
to facilitate privacy-preserving collaboration. Structured data, one of the most prevalent …
Performance of a machine learning algorithm using electronic health record data to identify and estimate survival in a longitudinal cohort of patients with lung cancer
Importance Electronic health records (EHRs) provide a low-cost means of accessing detailed
longitudinal clinical data for large populations. A lung cancer cohort assembled from EHR …
longitudinal clinical data for large populations. A lung cancer cohort assembled from EHR …
Effects of basicity and MgO content on the viscosity of the SiO2-CaO-MgO-9wt%Al2O3 slag system
Y Gao, S Wang, C Hong, X Ma, F Yang - International Journal of Minerals …, 2014 - Springer
The effects of basicity and MgO content on the viscosity of SiO 2 -CaO-MgO-9wt%Al 2 O 3
slags with basicity from 0.4 to 1.0 and MgO content from 13wt% to 19wt% were investigated …
slags with basicity from 0.4 to 1.0 and MgO content from 13wt% to 19wt% were investigated …