[HTML][HTML] Donation of mitochondria by iPSC-derived mesenchymal stem cells protects retinal ganglion cells against mitochondrial complex I defect-induced …
…, P Chen, B Yan, L Chen, K Gandhervin, C Ma… - Theranostics, 2019 - ncbi.nlm.nih.gov
Rationale: Retinal ganglion cell (RGC) degeneration is extremely hard to repair or
regenerate and is often coupled with mitochondrial dysfunction. Mesenchymal stem cells (MSCs)-…
regenerate and is often coupled with mitochondrial dysfunction. Mesenchymal stem cells (MSCs)-…
Translating mesenchymal stem cell and their exosome research into GMP compliant advanced therapy products: Promises, problems and prospects
CY Ma, Y Zhai, CT Li, J Liu, X Xu… - Medicinal Research …, 2023 - Wiley Online Library
… Chui-Yan Ma and Yuqing Zhai contributed equally to this study. … Chui-Yan Ma is a PhD
student at the Department of Medicine, The University of Hong Kong. She received her Bachelor's …
student at the Department of Medicine, The University of Hong Kong. She received her Bachelor's …
Mesenchymal stem cells for inflammatory airway disorders: promises and challenges
XL Fan, Z Zhang, CY Ma, QL Fu - Bioscience reports, 2019 - portlandpress.com
The regenerative and immunomodulatory characteristics of mesenchymal stem cells (MSCs)
make them attractive in the treatment of many diseases. Although they have shown …
make them attractive in the treatment of many diseases. Although they have shown …
[HTML][HTML] Modeling COVID-19 with human pluripotent stem cell-derived cells reveals synergistic effects of anti-inflammatory macrophages with ACE2 inhibition against …
…, BE Nilsson-Payant, P Wang, Z Zhang, CY Ma… - Research …, 2020 - ncbi.nlm.nih.gov
Dysfunctional immune responses contribute critically to the progression of Coronavirus
Disease-2019 (COVID-19) from mild to severe stages including fatality, with pro-inflammatory …
Disease-2019 (COVID-19) from mild to severe stages including fatality, with pro-inflammatory …
[PDF][PDF] Directed differentiation of notochord-like and nucleus pulposus-like cells using human pluripotent stem cells
Y Zhang, Z Zhang, P Chen, CY Ma, C Li, TYK Au… - Cell reports, 2020 - cell.com
Intervertebral disc degeneration might be amenable to stem cell therapy, but the required
cells are scarce. Here, we report the development of a protocol for directed in vitro …
cells are scarce. Here, we report the development of a protocol for directed in vitro …
[HTML][HTML] Management of adrenoleukodystrophy: From pre-clinical studies to the development of new therapies
CY Ma, C Li, X Zhou, Z Zhang, H Jiang, H Liu… - Biomedicine & …, 2021 - Elsevier
X-linked adrenoleukodystrophy (X-ALD) is an inherited neurodegenerative disorder associated
with mutations of the ABCD1 gene that encodes a peroxisomal transmembrane protein. …
with mutations of the ABCD1 gene that encodes a peroxisomal transmembrane protein. …
[HTML][HTML] Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model
…, P Motallebnejad, V Nicolaescu, J Chen, CY Ma… - Nature …, 2022 - nature.com
Dysfunctional immune responses contribute critically to the progression of Coronavirus
Disease-2019 (COVID-19), with macrophages as one of the main cell types involved. It is urgent …
Disease-2019 (COVID-19), with macrophages as one of the main cell types involved. It is urgent …
Distinct disease severity between children and older adults with coronavirus disease 2019 (COVID-19): impacts of ACE2 expression, distribution, and lung progenitor …
…, H Liang, Q Li, X Lu, X Wang, CY Ma… - Clinical Infectious …, 2021 - academic.oup.com
Background Children and older adults with coronavirus disease 2019 (COVID-19) display a
distinct spectrum of disease severity yet the risk factors aren’t well understood. We sought to …
distinct spectrum of disease severity yet the risk factors aren’t well understood. We sought to …
[PDF][PDF] Distinct disease severity between children and older adults with COVID-19: Impacts of ACE2 expression, distribution, and lung progenitor cells
Compared to children, ACE2 positive cells in the older adults are generally reduced and mainly
distributed in lower pulmonary tract. The lung progenitor cells are also decreased. These …
distributed in lower pulmonary tract. The lung progenitor cells are also decreased. These …
[HTML][HTML] Clinical analysis and pluripotent stem cells-based model reveal possible impacts of ACE2 and lung progenitor cells on infants vulnerable to COVID-19
…, J Shao, H Li, L Li, L Liu, C Li, J Zhang, CY Ma… - Theranostics, 2021 - ncbi.nlm.nih.gov
Introduction: An increasing number of children with severe coronavirus disease 2019 (COVID-19)
is being reported, yet the spectrum of disease severity and expression patterns of …
is being reported, yet the spectrum of disease severity and expression patterns of …