Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …

The inhibition of porcine pancreatic α-amylase and mammalian α-glucosidase by 16 individual
flavonoids was determined. The IC 50 values for baicalein, (+)-catechin, quercetin, and …

Ferroptosis is a new form of regulated cell death characterized by excessive iron accumulation
and uncontrollable lipid peroxidation. The role of ferroptosis in metabolic dysfunction-…

A DNA-encoded library is a collection of small molecules covalently linked to DNA that has
unique information about the identity and the structure of each library member. A DNA-…

Circular RNAs (circRNAs) represent a widespread class of non-coding RNAs generated
from back-splicing, with a circular loop structure. Many circRNAs have been reported to play …

Long noncoding RNAs (LncRNAs) act as crucial regulators in various cancers including
osteosarcoma (OS), yet their potential roles and molecular mechanisms in OS chemoresistance …

The catalytic cyclocondensation of in situ activated α,β‐unsaturated carboxylic acids was
developed. N‐heterocyclic carbenes efficiently catalyzed the generation of α,β‐unsaturated …

Three-component carboacylation of simple alkenes with readily available reagents is
challenging. Transition metal-catalysed intermolecular carboacylation works for alkenes with …

Recent efforts have revealed that numerous natural antisense lncRNAs play a crucial role in
the regulation of cancer biology. Here, based on our previous study, we further identified …

Chemo-resistance is a huge obstacle encountered in the osteosarcoma (OS) treatment.
Protein-coding mRNAs, as well as non-coding RNAs (ncRNAs), including long ncRNA (lncRNA), …