User profiles for Chung-Chau Hon

Chung-Chau, HON

Team Leader, Laboratory of Genome Information Analysis, Center for Life Science …
Verified email at riken.jp
Cited by 6706

An atlas of human long non-coding RNAs with accurate 5′ ends

CC Hon, JA Ramilowski, J Harshbarger, N Bertin… - Nature, 2017 - nature.com
Long non-coding RNAs (lncRNAs) are largely heterogeneous and functionally uncharacterized.
Here, using FANTOM5 cap analysis of gene expression (CAGE) data, we integrate …

An integrated expression atlas of miRNAs and their promoters in human and mouse

…, M Herlyn, P Heutink, KJ Hitchens, CC Hon… - Nature …, 2017 - nature.com
MicroRNAs (miRNAs) are short non-coding RNAs with key roles in cellular regulation. As part
of the fifth edition of the Functional Annotation of Mammalian Genome (FANTOM5) project, …

Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages

JJ Vasquez, CC Hon, JT Vanselow… - Nucleic acids …, 2014 - academic.oup.com
While gene expression is a fundamental and tightly controlled cellular process that is regulated
at multiple steps, the exact contribution of each step remains unknown in any organism. …

Evidence of the recombinant origin of a bat severe acute respiratory syndrome (SARS)-like coronavirus and its implications on the direct ancestor of SARS coronavirus

CC Hon, TY Lam, ZL Shi, AJ Drummond… - Journal of …, 2008 - Am Soc Microbiol
Bats have been identified as the natural reservoir of severe acute respiratory syndrome (SARS)-like
and SARS coronaviruses (SLCoV and SCoV). However, previous studies suggested …

Phylogeny-based evolutionary, demographical, and geographical dissection of North American type 2 porcine reproductive and respiratory syndrome viruses

M Shi, TTY Lam, CC Hon, MP Murtaugh… - Journal of …, 2010 - Am Soc Microbiol
Type 2 (or North American-like) porcine reproductive and respiratory syndrome virus (PRRSV)
was first recorded in 1987 in the United States and now occurs in most commercial swine …

Molecular epidemiology of PRRSV: a phylogenetic perspective

M Shi, TTY Lam, CC Hon, RKH Hui, KS Faaberg… - Virus research, 2010 - Elsevier
Since its first discovery two decades ago, porcine reproductive and respiratory syndrome
virus (PRRSV) has been the subject of intensive research due to its huge impact on the …

[HTML][HTML] Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to …

…, V Yadav, G Chatterjee, N Mullapudi, CC Hon… - PLoS …, 2014 - journals.plos.org
Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties (…

The single-cell eQTLGen consortium

…, DH de Vries, HE Groot, G Trynka, CC Hon… - elife, 2020 - elifesciences.org
In recent years, functional genomics approaches combining genetic information with bulk
RNA-sequencing data have identified the downstream expression effects of disease-…

Update of the FANTOM web resource: expansion to provide additional transcriptome atlases

…, A Kondo, A Hasegawa, CC Hon… - Nucleic acids …, 2019 - academic.oup.com
The FANTOM web resource ( http://fantom.gsc.riken.jp/ ) was developed to provide easy
access to the data produced by the FANTOM project. It contains the most complete and …

Functional annotation of human long noncoding RNAs via molecular phenotyping

…, ARR Forrest, R Guigó, MM Hoffman, CC Hon… - Genome …, 2020 - genome.cshlp.org
Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian
genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we …