User profiles for Chunlei Zheng

Chunlei Zheng

Boston University
Verified email at bu.edu
Cited by 1213

[HTML][HTML] A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories

D Placido, B Yuan, JX Hjaltelin, C Zheng, AD Haue… - Nature medicine, 2023 - nature.com
Pancreatic cancer is an aggressive disease that typically presents late with poor outcomes,
indicating a pronounced need for early detection. In this study, we applied artificial …

[HTML][HTML] Safety and pharmacokinetics of novel selective vascular endothelial growth factor receptor-2 inhibitor YN968D1 in patients with advanced malignancies

…, F Lv, K Jia, K Yv, F Wang, C Li, J Qian, C Zheng… - BMC cancer, 2010 - Springer
Background YN968D1 (Apatinib) selectively inhibits phosphorylation of VEGFR-2 and tumor
angiogenesis in mice model. The study was conducted to determine the maximum tolerated …

[HTML][HTML] Reduced Expression of METTL3 Promotes Metastasis of Triple-Negative Breast Cancer by m6A Methylation-Mediated COL3A1 Up-Regulation

Y Shi, C Zheng, Y Jin, B Bao, D Wang, K Hou… - Frontiers in …, 2020 - frontiersin.org
The abnormal m6A modification caused by m6A modulators is a common feature of various
tumors; however, little is known about which m6A modulator plays the most important role in …

Preparation of anion exchange membranes from BPPO and dimethylethanolamine for electrodialysis

MI Khan, C Zheng, AN Mondal, MM Hossain, B Wu… - Desalination, 2017 - Elsevier
In this research work, the synthesis of anion exchanges membranes (AEMs) from brominated
poly (2, 6-dimethyl-1, 4-phenylene oxide) (BPPO) and dimethyethanolamine (DMEA) has …

Study on hot deformation behaviour and processing maps of low carbon bainitic steel

Z Yang, F Zhang, C Zheng, M Zhang, B Lv… - Materials & Design (1980 …, 2015 - Elsevier
The hot deformation behaviour of low carbon bainitic steel, 29MnSiCrAlNiMo steel, was studied
at a temperature range of 800–1100 C and a strain rate range of 1 × 10 −2 to 1 × 10 1 s −…

GROUP: A Grid-Clustering Routing Protocol for Wireless Sensor Networks.

…, N Wang, W Zhang, C Zheng - … Conference on Wireless …, 2006 - ieeexplore.ieee.org
In this paper, we propose GROUP, a grid-clustering routing protocol that provides scalable
and efficient packet routing for large-scale wireless sensor networks. The sink proactively, …

Phosphorylated VEGFR2 and hypertension: potential biomarkers to indicate VEGF-dependency of advanced breast cancer in anti-angiogenic therapy

…, J Zhang, Z Wang, B Wang, Q Zhang, C Zheng… - Breast cancer research …, 2014 - Springer
The efficacy of anti-VEGF agents probably lies on VEGF-dependency. Apatinib, a specific
tyrosine kinase inhibitor that targets VEGF receptor 2, was assessed in patients with advanced …

[HTML][HTML] MAPK-activated protein kinase-2 (MK2)-mediated formation and phosphorylation-regulated dissociation of the signal complex consisting of p38, MK2, Akt …

C Zheng, Z Lin, ZJ Zhao, Y Yang, H Niu… - Journal of Biological …, 2006 - ASBMB
The p38 MAPK and heat shock protein 27 (hsp27) form a signaling complex with serine/threonine
kinase Akt and MAPK-activated protein kinase-2 (MK2), which plays an important role …

The COVID-19 hospitalization metric in the pre-and postvaccination eras as a measure of pandemic severity: A retrospective, nationwide cohort study

NR Fillmore, J La, C Zheng, S Doron, NV Do… - Infection Control & …, 2022 - cambridge.org
Background: Coronavirus disease 2019 (COVID-19) hospitalization definitions do not
include a disease severity assessment. Thus, we sought to identify a simple and objective …

Heat shock protein 27 downregulates the transferrin receptor 1-mediated iron uptake

H Chen, C Zheng, Y Zhang, YZ Chang, ZM Qian… - The international journal …, 2006 - Elsevier
It has been reported that over-expression of human heat shock protein 27 (hsp27) in murine
cells decreased the intracellular iron level [Arrigo, AP, Virot, S., Chaufour, S., Firdaus, W., …