Although the primary mechanism of eukaryotic messenger RNA decay is exoribonucleolytic
degradation in the 5′-to-3′ orientation, it has been widely accepted that Bacteria can only …

Ribonucleases play key, often essential, roles in cellular metabolism. Nineteen ribonuclease
activities, from 22 different proteins, have so far been described in bacteria, the majority of …

The control of rRNA synthesis in response to both extra- and intracellular signals has been
a subject of interest to microbial physiologists for nearly four decades, beginning with the …

Functional ribosomal RNAs are generated from longer precursor species in every organism
known. Maturation of the 5′ side of 16S rRNA in Escherichia coli is catalysed in a two‐step …

This review focuses on the enzymes and pathways of RNA processing and degradation in
Bacillus subtilis, and compares them to those of its gram-negative counterpart, Escherichia coli…

Transfer RNAs (tRNAs) are synthesized as part of longer primary transcripts that require
processing of both their 3′ and 5′ extremities in every living organism known. The 5′ side is …

Escherichia coli ribosomal RNA (rRNA) operons contain antitermination motifs necessary
for forming terminator‐resistant transcription complexes. In preliminary work, we isolated ‘…

Ribonucleases J1 and J2 are recently discovered enzymes with dual 5′‐to‐3′
exoribonucleolytic/endoribonucleolytic activity that plays a key role in the maturation and …

The Escherichia coli genome carries seven rRNA (rrn) operons, each containing three rRNA
genes. The presence of multiple operons has been an obstacle to many studies of rRNA …

Here we present evidence that only five of the seven rRNA operons present in Escherichia
coli are necessary to support near-optimal growth on complex media. Seven rrn operons are …