[HTML][HTML] Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria
Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism,
ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have …
ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have …
[HTML][HTML] Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome
…, I Mathieson, WL McCardle, Y Louwers, C Meun… - Nature …, 2015 - nature.com
Polycystic ovary syndrome (PCOS) is the most common reproductive disorder in women, yet
there is little consensus regarding its aetiology. Here we perform a genome-wide …
there is little consensus regarding its aetiology. Here we perform a genome-wide …
Associations of steroid sex hormones and sex hormone–binding globulin with the risk of type 2 diabetes in women: a population-based cohort study and meta …
It remains unclear whether endogenous sex hormones (ESH) are associated with risk of
type 2 diabetes (T2D) in women. Data of 3,117 postmenopausal women participants of the …
type 2 diabetes (T2D) in women. Data of 3,117 postmenopausal women participants of the …
Health in middle-aged and elderly women: a conceptual framework for healthy menopause
…, GM Van Dijk, T Gazibara, T Muka, K Wen, C Meun… - Maturitas, 2015 - Elsevier
Middle-aged and elderly women constitute a large and growing proportion of the population.
The peri and postmenopausal period constitutes a challenging transition time for women's …
The peri and postmenopausal period constitutes a challenging transition time for women's …
High androgens in postmenopausal women and the risk for atherosclerosis and cardiovascular disease: the Rotterdam study
Context Polycystic ovary syndrome (PCOS) is closely linked to hyperandrogenism (HA). In
PCOS, HA has been associated with metabolic disturbances that increase the risk for …
PCOS, HA has been associated with metabolic disturbances that increase the risk for …
Cardiovascular risk in women with premature ovarian insufficiency compared to premenopausal women at middle age
…, JSE Laven, CGKM Fauser, C Meun… - The Journal of …, 2016 - academic.oup.com
Context: A young age at menopause has been associated with increased cardiovascular
disease (CVD) risk. Objective: To compare the cardiovascular risk profile between women with …
disease (CVD) risk. Objective: To compare the cardiovascular risk profile between women with …
Prevalence of subclinical coronary artery disease assessed by coronary computed tomography angiography in 45-to 55-year-old women with a history of …
…, A Van Der Lugt, A Maassen van den Brink, C Meun… - Circulation, 2018 - Am Heart Assoc
We included 164 asymptomatic women with a history of preeclampsia (mean age, 48.4±2.9
years at inclusion). Overall, 31% presented with a CACS> 0 and 17% had CACS≥ 95th …
years at inclusion). Overall, 31% presented with a CACS> 0 and 17% had CACS≥ 95th …
The cardiovascular risk profile of middle‐aged women with polycystic ovary syndrome
C Meun, MN Gunning, YV Louwers… - Clinical …, 2020 - Wiley Online Library
Objectives Contradictory results have been reported regarding the association between
polycystic ovary syndrome (PCOS) and cardiovascular disease (CVD). We assessed the …
polycystic ovary syndrome (PCOS) and cardiovascular disease (CVD). We assessed the …
A polygenic and phenotypic risk prediction for polycystic ovary syndrome evaluated by phenome-wide association studies
…, T Karaderi, FD Mentch, C Meun… - The Journal of …, 2020 - academic.oup.com
Context As many as 75% of patients with polycystic ovary syndrome (PCOS) are estimated
to be unidentified in clinical practice. Objective Utilizing polygenic risk prediction, we aim to …
to be unidentified in clinical practice. Objective Utilizing polygenic risk prediction, we aim to …
[HTML][HTML] Antimüllerian hormone to determine polycystic ovarian morphology
AD de Loos, M Hund, K Buck, C Meun, J Sillman… - Fertility and sterility, 2021 - Elsevier
Objective To determine a cutoff for the Elecsys AMH Plus immunoassay (Roche Diagnostics
International Ltd, Rotkreuz, Switzerland) to identify polycystic ovarian morphology (PCOM), …
International Ltd, Rotkreuz, Switzerland) to identify polycystic ovarian morphology (PCOM), …