Plants are foundational for global ecological and economic systems, but most plant proteins
remain uncharacterized. Protein interaction networks often suggest protein functions and …

Macromolecular protein complexes carry out many of the essential functions of cells, and
many genetic diseases arise from disrupting the functions of such complexes. Currently, there …

The R package colorspace provides a flexible toolbox for selecting individual colors or color
palettes, manipulating these colors, and employing them in statistical graphics and data …

Chloroplasts are eukaryotic photosynthetic organelles that drive the global carbon cycle.
Despite their importance, our understanding of their protein composition, function, and spatial …

Our previous data suggested that the human basic helix–loop–helix transcription factor
achaete-scute homologue-1 (hASH1) may stimulate both proliferation and migration in the lung. …

Correctly estimating the age of a gene or gene family is important for a variety of fields,
including molecular evolution, comparative genomics, and phylogenetics, and increasingly for …

Multiple sequence alignment (MSA) is a critical step in the study of protein sequence and
function. Typically, MSA algorithms progressively align pairs of sequences and combine these …

Photosynthesis is central to food production and the Earth's biogeochemistry, yet the molecular
basis for its regulation remains poorly understood. Here, using high-throughput genetics …

10.7554/eLife.25093.001 Eukaryotes and prokaryotes last shared a common ancestor ~2
billion years ago, and while many present-day genes in these lineages predate this divergence…

Clinical influenza A virus isolates are frequently not sequenced directly. Instead, a majority
of these isolates (∼70% in 2015) are first subjected to passaging for amplification, most …