[HTML][HTML] Extracellular forces cause the nucleus to deform in a highly controlled anisotropic manner
K Haase, JKL Macadangdang, CH Edrington… - Scientific reports, 2016 - nature.com
Physical forces arising in the extra-cellular environment have a profound impact on cell fate
and gene regulation; however the underlying biophysical mechanisms that control this …
and gene regulation; however the underlying biophysical mechanisms that control this …
[PDF][PDF] Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization
The cytoplasm is a crowded, visco-elastic environment whose physical properties change
according to physiological or developmental states. How the physical properties of the …
according to physiological or developmental states. How the physical properties of the …
Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization
The cytoplasm represents a crowded environment whose properties may change according
to physiological or developmental states. Although the effects of crowding and viscosity on …
to physiological or developmental states. Although the effects of crowding and viscosity on …
Doublecortin engages the microtubule lattice through a cooperative binding mode involving its C-terminal domain
A Rafiei, SC Tetlalmatzi, CH Edrington, L Lee… - Elife, 2022 - elifesciences.org
Doublecortin (DCX) is a microtubule (MT)-associated protein that regulates MT structure
and function during neuronal development and mutations in DCX lead to a spectrum of …
and function during neuronal development and mutations in DCX lead to a spectrum of …
[HTML][HTML] Distinct functional roles for the M4 α-helix from each homologous subunit in the heteropentameric ligand-gated ion channel nAChR
MJ Thompson, JA Domville, CH Edrington… - Journal of Biological …, 2022 - ASBMB
The outermost lipid-exposed α-helix (M4) in each of the homologous α, β, δ, and γ/ε subunits
of the muscle nicotinic acetylcholine receptor (nAChR) has previously been proposed to act …
of the muscle nicotinic acetylcholine receptor (nAChR) has previously been proposed to act …
Biochemical modulation of microtubule dynamic instability
CH Edrington - 2023 - search.proquest.com
Microtubules are an essential component of the cytoskeleton. These long slender tubes made
of α/β-tubulin dimers are involved in cell division, migration and differentiation. They are …
of α/β-tubulin dimers are involved in cell division, migration and differentiation. They are …
[PDF][PDF] Physical properties of the cytoplasm modulate the rates of microtubule polymerization and
…, J Lemière, M Gazzola, EI Steinmark, CH Edrington - macromolecules - scholar.archive.org
The cytoplasm is a crowded, visco-elastic environment whose physical properties change
according to physiological or developmental states. How the physical properties of the …
according to physiological or developmental states. How the physical properties of the …
[PDF][PDF] Cytoplasm Biophysical Properties Limit Cytoskeleton Dynamics In Vivo
AT Molines, J Lemiere, CH Edrington, CT Hsu… - Biophysical …, 2021 - cell.com
The cytoplasm is a very crowded environment harboring most of the metabolic reactions
necessary for cellular function. Its biophysical properties are influenced by cellular metabolism. …
necessary for cellular function. Its biophysical properties are influenced by cellular metabolism. …
Autophagy in the eye: implications for ocular cell health
LS Frost, CH Mitchell, K Boesze-Battaglia - Experimental eye research, 2014 - Elsevier
Autophagy, a catabolic process by which a cell “eats” itself, turning over its own cellular
constituents, plays a key role in cellular homeostasis. In an effort to maintain normal cellular …
constituents, plays a key role in cellular homeostasis. In an effort to maintain normal cellular …
Admission blood glucose level and its association with cardiovascular and renal complications in patients hospitalized with COVID-19
OBJECTIVE To investigate the association between admission blood glucose levels and
risk of in-hospital cardiovascular and renal complications. RESEARCH DESIGN AND …
risk of in-hospital cardiovascular and renal complications. RESEARCH DESIGN AND …