Here we report a high-quality draft genome sequence of the domestic dog (Canis familiaris),
together with a dense map of single nucleotide polymorphisms (SNPs) across breeds. The …

Genomewide association mapping in model organisms such as inbred mouse strains is a
promising approach for the identification of risk factors related to human diseases. However, …

Ustilago maydis is a ubiquitous pathogen of maize and a well-established model organism
for the study of plant–microbe interactions 1 . This basidiomycete fungus does not use …

We report a high-quality draft of the genome sequence of the grey, short-tailed opossum (Monodelphis
domestica). As the first metatherian (‘marsupial’) species to be sequenced, the …

With several hundred genetic diseases and an advantageous genome structure, dogs are
ideal for mapping genes that cause disease. Here we report the development of a genotyping …

A dense map of genetic variation in the laboratory mouse genome will provide insights into
the evolutionary history of the species 1 and lead to an improved understanding of the …

Most inbred laboratory mouse strains are known to have originated from a mixed but limited
founder population in a few laboratories 1 , 2 . However, the effect of this breeding history on …

Canine degenerative myelopathy (DM) is a fatal neurodegenerative disease prevalent in
several dog breeds. Typically, the initial progressive upper motor neuron spastic and general …

Intense selective pressures applied over short evolutionary time have resulted in homogeneity
within, but substantial variation among, horse breeds. Utilizing this population structure, …

An equine SNP genotyping array was developed and evaluated on a panel of samples
representing 14 domestic horse breeds and 18 evolutionarily related species. More than 54,000 …