Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension

…, RNO Da Silva, Z Cao, D Graham, C McMaster… - …, 2018 - Am Heart Assoc
Vascular Nox (NADPH oxidase)-derived reactive oxygen species and endoplasmic reticulum
(ER) stress have been implicated in hypertension. However, relationships between these …

Radical-mediated reduction of the dithiocarbamate group under tin-free conditions

C McMaster, RN Bream, RS Grainger - Organic & Biomolecular …, 2012 - pubs.rsc.org
Reductive desulfurisation of dithiocarbamates is conveniently achieved using H3PO2–Et3N–ACCN
in refluxing dioxane. Fused and spirocyclic β-lactams, prepared through 4-exo trig …

[PDF][PDF] The hepatic compensatory response to elevated systemic sulfide promotes diabetes

…, T Gillingwater, KH Ahn, S Singha, C McMaster… - Cell Reports, 2021 - cell.com
Impaired hepatic glucose and lipid metabolism are hallmarks of type 2 diabetes. Increased
sulfide production or sulfide donor compounds may beneficially regulate hepatic metabolism. …

Solid-phase synthesis of anagrelide sulfonyl analogues

C McMaster, V Fülöpová, I Popa… - ACS Combinatorial …, 2014 - ACS Publications
Simple solid-phase synthesis of 3,10-dihydro-2H-benzo[e]imidazo[1,2-b][1,2,4]thiadiazin-2-one
5,5-dioxides is described, with Fmoc-α-amino acids and 2-nitrobenzenesulfonyl …

Preparation of 2-phenyl-3-hydroxyquinoline-4 (1 H)-one-5-carboxamides as potential anticancer and fluorescence agents

…, P Džubák, P Znojek, S Gurská, J Kusz, C McMaster… - RSC Advances, 2015 - pubs.rsc.org
The synthesis of 3-hydroxyquinoline-4(1H)-one derivatives bearing substituted phenyl in
position 2 and variously substituted carboxamide group in position 5 is described, with use of 3-…

Synthesis of Novel N9-Substituted Purine Derivatives from Polymer Supported α-Amino Acids

…, T Volna, V Krystof, C McMaster… - ACS combinatorial …, 2015 - ACS Publications
Solid-phase synthesis of purine derivatives bearing an α-amino acid motif in position 9 is
described herein. Polymer supported amines were acylated with various Fmoc-α-amino acids …

Solid‐Phase Synthesis of Trisubstituted Benzo[f][1,2,3]triazolo[1,5‐a][1,4]diazepin‐6(5H)‐ones and Their Sulfonyl Analogues under Mild Reaction Conditions

…, P Funk, I Popa, C McMaster… - European Journal of …, 2015 - Wiley Online Library
The solid‐phase synthesis of 4H‐benzo[f][1,2,3]triazolo[1,5‐a][1,4]diazepin‐6(5H)‐ones and
4,5‐dihydrobenzo[f][1,2,3]triazolo[5,1‐d][1,2,5]thiadiazepine 6,6‐dioxides under mild and …

[HTML][HTML] Canadian Arctic contaminants and their effects on the maternal brain and behaviour: A scoping review of the animal literature

C Fong-McMaster, S Konji, A Nitschke… - International Journal of …, 2020 - mdpi.com
Background: Environmental toxicants such as methylmercury, polychlorinated biphenyls, and
organochlorine pesticides are potentially harmful pollutants present in contaminated food, …

The uptake of avermectins in Caenorhabditis elegans is dependent on Intra-Flagellar Transport and other protein trafficking pathways

RA Brinzer, DJ France, C McMaster, S Ruddell… - bioRxiv, 2021 - biorxiv.org
Parasitic nematodes are globally important and place a heavy disease burden on infected
humans, crops and livestock, while commonly administered anthelmintics used for treatment …

[HTML][HTML] The TNFα/TNFR2 axis mediates natural killer cell proliferation by promoting aerobic glycolysis

…, D Jo, S Ahmadvand, C Fong-McMaster… - Cellular & Molecular …, 2023 - nature.com
Natural killer (NK) cells are predominant innate lymphocytes that initiate the early immune
response during infection. NK cells undergo a metabolic switch to fuel augmented …