Genome-wide association studies (GWAS) and large-scale replication studies have identified
common variants in 79 loci associated with breast cancer, explaining ∼14% of the familial …

Antitumor immunity driven by intratumoral dendritic cells contributes to the efficacy of
anthracycline-based chemotherapy in cancer. We identified a loss-of-function allele of the gene …

Purpose: Markers of chemotherapy efficacy in metastatic colorectal cancer (mCRC) are
essential for optimization of treatment strategies. We evaluated the applicability of early changes …

Purpose The aim was to investigate whether germline polymorphisms within candidate
genes known or suspected to be involved in fluorouracil (FU), oxaliplatin, and irinotecan …

Night shift work has been associated with an increased risk of breast cancer pointing to a
role of circadian disruption. We investigated the role of circadian clock gene polymorphisms …

Two genome‐wide association studies (GWASs) recently highlighted the HLA‐DRA and
HLA‐DRB5 genes as associated with Parkinson disease (PD). However, because HLA‐DRA …

BACKGROUND Circulating tumor DNA (ctDNA) has emerged as a good candidate for tracking
tumor dynamics in different cancer types, potentially avoiding repeated tumor biopsies. …

Candidate variant association studies have been largely unsuccessful in identifying common
breast cancer susceptibility variants, although most studies have been underpowered to …

Purpose: Circulating tumor DNA (ctDNA) has been suggested as a major prognostic factor in
resected stage-III colon cancer. We analyzed ctDNA of patients randomized in the phase III …

Alternative sources such as buccal cells have already been tested for genetic studies and
epidemiological investigations. Thirty-seven volunteers participated in this study to compare …