Many genome variants shaping mammalian phenotype are hypothesized to regulate gene
transcription and/or to be under selection. However, most of the evidence to support this …

Genetic variants which affect complex traits (causal variants) are thought to be found in
functional regions of the genome. Identifying causal variants would be useful for predicting …

Background Causal variants for complex traits, such as eQTL are often found in non-coding
regions of the genome, where they are hypothesised to influence phenotypes by regulating …

Background Mammalian phenotypes are shaped by numerous genome variants, many of
which may regulate gene transcription or RNA splicing. To identify variants with regulatory …

Background The use of whole-genome sequence (WGS) data for genomic prediction and
association studies is highly desirable because the causal mutations should be present in the …

Allele specific expression (ASE) is widespread in many species including cows. Therefore,
regulatory regions which control gene expression should show cis-regulatory variation which …

Feed efficiency and energy balance are important traits underpinning profitability and
environmental sustainability in animal production. They are complex traits, and our understanding …

Context Functional genomics studies have highlighted genomic regions with regulatory and
evolutionary significance. Such information independent of association analysis may benefit …

“Enrichment (C/A)/(B/D) where: A is the number of positions under peaks, B is the number of
positions that were putative causal SNPs, C is the number of positions under peaks and …

MicroRNAs regulate many eukaryotic biological processes in a temporal- and spatial-specific
manner. Yet in cattle it is not fully known which microRNAs are expressed in each tissue, …