Genomics has set the basis for a variety of methodologies that produce high-throughput
datasets identifying the different players that define gene regulation, particularly regulation of …

Breast cancer stem cells (bCSCs) have been implicated in tumor progression and therapeutic
resistance; however, the molecular mechanisms that define this state are unclear. We …

Therapeutic resistance is a major clinical challenge in oncology. Evidence identifies cancer
stem cells ( CSC s) as a driver of tumor evolution. Accordingly, the key stemness property …

We designed a PyQt graphical user interface—Sequanix—aimed at democratizing the use
of Snakemake pipelines in the NGS space and beyond. By default, Sequanix includes …

The plant-dedicated mirror of the Regulatory Sequence Analysis Tools (RSAT, http://plants.rsat.eu
) offers specialized options for researchers dealing with plant transcriptional regulation…

Post-genomic implementations have expanded the experimental strategies to identify elements
involved in the regulation of transcription initiation. Here, we present for the first time a …

Our previous transcriptomic analysis of Glossina palpalis gambiensis experimentally infected
or not with Trypanosoma brucei gambiense aimed to detect differentially expressed genes (…

High-throughput RNAi screenings (HTS) allow quantifying the impact of the deletion of each
gene in any particular function, from virus-host interactions to cell differentiation. However, …

Post-genomic implementations have expanded the experimental strategies to identify
elements involved in the regulation of transcription initiation. As new methodologies emerge, a …

In this protocol, we explain how to run ab initio motif discovery in order to gather putative
transcription factor binding motifs (TFBMs) from sets of genomic regions returned by ChIP-seq …