[HTML][HTML] Modeling liver organogenesis by recreating three-dimensional collective cell migration: a role for TGFβ pathway

…, C Ott, A Kalinousky, W Lin, C Shamul… - … in Bioengineering and …, 2021 - frontiersin.org
Three-dimensional (3D) collective cell migration (CCM) is critical for improving liver cell
therapies, eliciting mechanisms of liver disease, and modeling human liver development and …

Spatiotemporal imaging and analysis of mouse and human liver bud morphogenesis

O Ogoke, D Guiggey, T Mon, C Shamul… - Developmental …, 2022 - Wiley Online Library
Background The process of liver organogenesis has served as a paradigm for organ formation.
However, there remains a lack of understanding regarding early mouse and human liver …

Dynamic changes in the niche and transcription trigger early murine and human pluripotent stem cell-derived liver organogenesis

…, THA Nguyen, D Berke, C Ott, A Kalinousky, C Shamul… - bioRxiv, 2022 - biorxiv.org
Organoids bearing human stem cell-derived progenitors enable basic and applied investigation
of organogenesis in a wide range of epithelial tissues. During liver organogenesis (LO), …

High resolution, serial imaging of early mouse and human liver bud morphogenesis in three dimensions

O Ogoke, D Guiggey, T Mon, C Shamul, S Ross, S Rao… - bioRxiv, 2019 - biorxiv.org
Background Liver organogenesis has thus far served as a paradigm for solid organ formation.
The developing liver bud is a well established model of organogenesis, and murine …

Mesenchyme modulates three-dimensional, collective cell migration of liver cells in vitro - a role for TGFß pathway

…, O Yousef, C Ott, A Kalinousky, L Wayne, C Shamul… - bioRxiv, 2020 - biorxiv.org
Three dimensional (3D) collective cell migration (CCM) is critical for improving liver cell
therapies, eliciting mechanisms of liver disease, and modeling human liver development/ …

[CITATION][C] Role of Tissue Geometry in Regulating Liver Bud Morphogenesis

C Shamul, S Ross, W Lin, O Yousef, C Ott… - 2019 AIChE Annual …, 2019 - aiche.confex.com

Bioengineered 3D Models of Hepatic Cell Migration for Applications in Liver Regenerative Medicine

O Ogoke - 2020 - search.proquest.com
The liver serves as the largest internal organ, responsible for a myriad of homeostatic and
metabolic regulatory functions. The liver remains as the only internal organ to retain the ability …

Regulating Endodermal Cell Lineage through Genetic Manipulation of Developmental Regulatory Gene Circuits (DRGC's)

I Warren - 2020 - search.proquest.com
… undergraduates such as Kristen Place, Casey Grosso, Laura Zu, and Claire Shamul, with
emphasis on Ryan Thompson and Peter Chen for their dedicated support to my project. …

[PDF][PDF] Humanizing Therapeutics Discovery & Development

DA Laufenburger - engineering.buffalo.edu
Membrane technology has emerged as a potentially economically viable alternative for CO2
captures from fossil fuel-fired powers, enabled by advanced membrane materials with high …

[HTML][HTML] Multi and transgenerational epigenetic effects of di-(2-ethylhexyl) phthalate (DEHP) in liver

Y Wen, S Rattan, JA Flaws, J Irudayaraj - Toxicology and applied …, 2020 - Elsevier
Di-(2-ethylhexyl) phthalate (DEHP), a ubiquitous industrial pollutant, is a known endocrine
disrupter implicated in metabolic diseases. Prenatal DEHP exposure promotes epigenetic …