[HTML][HTML] Cross-reactive SARS-CoV-2 neutralizing antibodies from deep mining of early patient responses

…, I Diamantopoulos, K Parthiban, C Tebbutt… - Frontiers in …, 2021 - frontiersin.org
Passive immunization using monoclonal antibodies will play a vital role in the fight against
COVID-19. The recent emergence of viral variants with reduced sensitivity to some current …

Human cell surface-AAV interactomes identify LRP6 as blood-brain-barrier transcytosis receptor and immune cytokine IL3 as AAV9 binder

TF Shay, S Jang, X Chen, B Walker, C Tebbutt… - bioRxiv, 2024 - biorxiv.org
Adeno-associated viruses (AAVs) are foundational gene delivery tools for basic science
and clinical therapeutics. However, lack of mechanistic insight, especially for engineered …

Deep mining of early antibody response in COVID-19 patients yields potent neutralisers and reveals high level of convergence

…, R Brown, I Diamantopoulos, K Parthiban, C Tebbutt… - bioRxiv, 2020 - biorxiv.org
Passive immunisation using monoclonal antibodies will play a vital role in the fight against
COVID-19. Until now, the majority of anti-SARS-CoV-2 antibody discovery efforts have relied …

MPL-5821, a macrophage targeted ESMTM p38 MAPK inhibitor, inhibits the production of TLR agonist induced IL-10 whilst sparing T-cell functionality

…, L Janicova, A Nika, D Turner, C Doris, C Tebbutt… - Cancer Research, 2018 - AACR
Compensatory release of immunosuppressive cytokines, such as IL-10, by macrophages
present in the tumor microenvironment has been implicated as a mechanism for adaptive …

Accessible Aid, Inaccessible Conditions: The Effects of International Aid on the Deinstitutionalization of Children with Disabilities in Bulgaria

CE Tebutt - 2023 - repository.library.georgetown.edu
Policymakers, advocates, and service providers of the disability community call for increased
allocation of resources and funding towards deinstitutionalization, or the process of moving …

Being boys: Youth, leisure and identity in the inter-war years

M Tebbutt - Being boys, 2017 - manchesterhive.com
… The right of Melanie Tebbutt to be identified as the author of this work has been asserted
by … The main absence in this list of thanks is my father, Les Tebbutt, who died in 1997. The …

[BOOK][B] Making youth: a history of youth in modern Britain

M Tebbutt - 2017 - books.google.com
… Highlighting both change and striking continuity, Melanie Tebbutt traces the origins and
development of key themes and debates in the history of modern British youth. Current issues …

IKKε and TBK1 in diffuse large B‐cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF‐κB and IL‐10 signalling

M Carr, S Mamand, KL Chapman… - Journal of Cellular …, 2020 - Wiley Online Library
The IKK‐related kinases, IKKε and TBK1, have essential roles in innate immunity in part
through modifying MYD88 signalling from the Toll‐like receptors to regulate NF‐κB signalling. …

Crying for Flicka: Boys, Young Men, and Emotion at the Cinema in Britain in the 1930s and 1940s

M Tebbutt - Journal of Social History, 2022 - academic.oup.com
This article re-visits contemporary surveys of the cinema in the 1930s and 1940s to explore
the implications that the cinema’s role as an “emotional frontier” between everyday life and …

From 'marriage bureau'to 'points of view': Changing patterns of advice in teenage magazines: Mirabelle, 1956–77

M Tebbutt - People, places and identities, 2017 - manchesterhive.com
Comics and teenage magazines were an important part of girls’ culture between the 1950s
and late 1970s. They ranged from popular pre-teen comics like Bunty and Judy (first …