Patients with chronic kidney disease (CKD) are at an increased risk of premature mortality,
mainly from cardiovascular causes. The association between CKD on hemodialysis and …

Angiotensin-converting enzyme 2 (ACE2) is an enzymatically active homologue of
angiotensin-converting enzyme that degrades angiotensin I, angiotensin II, and other peptides. …

Introducción: Las proteínas presentan una eliminación variable a lo largo del día; por ello
clásicamente se ha considerado la proteinuria de 24 horas como el método de referencia …

Background Hepatitis C virus (HCV)‐associated mixed cryoglobulinaemia is the manifestation
of an inflammation of small and medium‐sized vessels produced by a pathogenic IgM …

Angiotensin (Ang)-converting enzyme 2 (ACE2) cleaves Ang II to form Ang-(1-7). Here we
examined whether soluble human recombinant ACE2 (rACE2) can efficiently lower Ang II and …

Antecedentes y objetivos La afectación renal del diabético solo puede determinarse mediante
biopsia renal, que presenta una elevada prevalencia de lesiones no diabéticas. Los …

Objective Glycans attached to the Fc portion of IgG are important modulators of IgG effector
functions. Interindividual differences in IgG glycome composition are large and they …

Introduction Several circulating metabolites derived from bacterial protein fermentation have
been found to be inversely associated with renal function but the timing and disease …

Small molecules are extensively metabolized and cleared by the kidney. Changes in serum
metabolite concentrations may result from impaired kidney function and can be used to …

Background Sparsentan, a novel, non-immunosuppressive, single-molecule, dual endothelin
angiotensin receptor antagonist, significantly reduced proteinuria versus irbesartan, an …