User profiles for Clarissa B. Haas
 | Clarissa Branco Haas, PharmD, PhDClinical Trial Liaison Verified email at iconplc.com Cited by 808 |
[HTML][HTML] Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature
Background Preprint usage is growing rapidly in the life sciences; however, questions
remain on the relative quality of preprints when compared to published articles. An objective …
remain on the relative quality of preprints when compared to published articles. An objective …
Exercise increases insulin signaling in the hippocampus: physiological effects and pharmacological impact of intracerebroventricular insulin administration in mice
Increasing evidence indicates that physical exercise induces adaptations at the cellular,
molecular, and systemic levels that positively affect the brain. Insulin plays important functional …
molecular, and systemic levels that positively affect the brain. Insulin plays important functional …
Brain insulin administration triggers distinct cognitive and neurotrophic responses in young and aged rats
Aging is a major risk factor for cognitive deficits and neurodegenerative disorders, and impaired
brain insulin receptor (IR) signaling is mechanistically linked to these abnormalities. The …
brain insulin receptor (IR) signaling is mechanistically linked to these abnormalities. The …
Hyperpalatable diet and physical exercise modulate the expression of the glial monocarboxylate transporters MCT1 and 4
LV Portela, AW Brochier, CB Haas… - Molecular …, 2017 - Springer
Hyperpalatable diets (HP) impair brain metabolism, and regular physical exercise has an
apparent opposite effect. Here, we combined a prior long-term exposure to HP diet followed by …
apparent opposite effect. Here, we combined a prior long-term exposure to HP diet followed by …
Physical Exercise Exacerbates Memory Deficits Induced by Intracerebroventricular STZ but Improves Insulin Regulation of H 2O 2 Production in Mice Synaptosomes
Insulin brain resistant state is associated with cognitive deficits and Alzheimer’s disease by
mechanisms that may involve mitochondrial damage and oxidative stress. Conversely, …
mechanisms that may involve mitochondrial damage and oxidative stress. Conversely, …
Extracellular ectonucleotidases are differentially regulated in murine tissues and human polymorphonuclear leukocytes during sepsis and inflammation
Sepsis is life-threatening organ dysfunction caused by a dysregulated inflammatory and
immune response to infection. Sepsis involves the combination of exaggerated inflammation …
immune response to infection. Sepsis involves the combination of exaggerated inflammation …
[PDF][PDF] High resolution respirometry (HRR) as an experimental tool to analyze oxygen metabolism and mitochondrial physiology in murine microglia
CB Haas, BJL Eggen - Insulin signaling and microglia in the young …, 2021 - research.rug.nl
Similar to peripheral macrophages, microglia are phagocytic cells that are constantly re-structuring
their actin-microtubule cytoskeleton upon surveillance and migration through the …
their actin-microtubule cytoskeleton upon surveillance and migration through the …
[PDF][PDF] The effects of Insulin on murine microglia metabolism and cytokine expression in vitro and in vivo
CB Haas, BJL Eggen - Insulin signaling and microglia in the young …, 2021 - research.rug.nl
Microglia are the tissue-resident macrophages of the CNS, with specialized roles that are
shaped by their neural microenvironment and go beyond immunological functions. Insulin is a …
shaped by their neural microenvironment and go beyond immunological functions. Insulin is a …
Ectonucleoside Triphosphate Diphosphohydrolase 8 Contributes to Bacterial Growth and Inflammation in Polymicrobial Sepsis
ZH Nemeth, CBB Haas, LT DiFazio… - Journal of the …, 2020 - journals.lww.com
METHODS: The immunological status of septic animals was assessed by measuring
bacterial clearance, cytokine levels, markers of organ functions at 6 and 16 hours after cecal …
bacterial clearance, cytokine levels, markers of organ functions at 6 and 16 hours after cecal …
Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature
BackgroundPreprint usage is growing rapidly in the life sciences; however, questions
remain on the relative quality of preprints when compared to published articles. An objective …
remain on the relative quality of preprints when compared to published articles. An objective …