Adenovirus type 5 SARS-CoV-2 vaccines delivered orally or intranasally reduced disease severity and transmission in a hamster model

SN Langel, S Johnson, CI Martinez… - Science Translational …, 2022 - science.org
Transmission-blocking strategies that slow the spread of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and protect against coronavirus disease 2019 (COVID-19) are …

Oral vaccination protects against severe acute respiratory syndrome coronavirus 2 in a Syrian hamster challenge model

S Johnson, CI Martinez… - The Journal of …, 2022 - academic.oup.com
Background Vaccines that are shelf stable and easy to administer are crucial to improve
vaccine access and reduce severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

SARS-CoV-2 oral tablet vaccination induces neutralizing mucosal IgA in a phase 1 open label trial

S Johnson, CI Martinez, CB Jegede, S Gutierrez… - MedRxiv, 2022 - medrxiv.org
Background Despite the plethora of efficacious vaccines to the initial Wuhan strain of SARS-CoV-2,
these do not induce robust mucosal immunity, offering limited protection against …

[HTML][HTML] Mucosal immunization with Ad5-based vaccines protects Syrian hamsters from challenge with omicron and delta variants of SARS-CoV-2

MR Braun, CI Martinez, EG Dora, LJ Showalter… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2 variant clades continue to circumvent antibody responses elicited by vaccination
or infection. Current parenteral vaccination strategies reduce illness and hospitalization, …

Oral and intranasal Ad5 SARS-CoV-2 vaccines decrease disease and viral transmission in a golden hamster model

SN Langel, S Johnson, CI Martinez, SN Tedjakusuma… - BioRxiv, 2021 - biorxiv.org
Transmission-blocking strategies that slow the spread of SARS-CoV-2 and protect against
COVID-19 are needed. We have developed a shelf-stable, orally-delivered Ad5-vectored …

Mucosal immunization of cynomolgus macaques with adenoviral vector vaccine elicits neutralizing nasal and serum antibody to several SARS-CoV-2 variants

…, EG Dora, N Peinovich, M Cortese, CI Martinez… - bioRxiv, 2022 - biorxiv.org
The emergence of SARS-CoV-2 variants continues to be a major obstacle for controlling the
global pandemic. Despite the currently authorized SARS-CoV-2 vaccines ability to reduce …

Complete genome sequences and characteristics of mycobacteriophages Diminimus, Dulcita, Glaske16, and Koreni

…, KE Mathews, EG Livingston, CA Martinez… - Microbiology …, 2024 - Am Soc Microbiol
Complete genome sequences of four novel mycobacteriophages, Diminimus, Dulcita,
Glaske16, and Koreni, isolated from soil are presented. All these bacteriophages belong to …

PERCEIVED FINANCIAL STRAIN AND ITS EFFECTS ON COLLEGE STUDENTS'WELFARE

M Contreras, CA Martinez - 2023 - scholarworks.lib.csusb.edu
This study examined the relationship between perceived financial strain and the physical,
mental/emotional, and social well-being of students in college. The quantitative study used …

[HTML][HTML] Consistent linear and non-linear responses to invasive electrical brain stimulation across individuals and primate species with implanted electrodes

…, H Deng, M Thombs, C Martinez-Rubio… - Brain stimulation, 2019 - Elsevier
Background Electrical neuromodulation via implanted electrodes is used in treating numerous
neurological disorders, yet our knowledge of how different brain regions respond to …

NOSH-aspirin and 5-fluorouracil demonstrate synergistic efficacy in a xenograft model of colon cancer

CJ Martinez, M Chattopadhyay, K Kashfi - Cancer Research, 2014 - AACR
Introduction: Work in cancer biology, epidemiology and preclinical models has made it clear
that non-steroidal anti-inflammatory drugs (NSAIDs) in general and aspirin in particular can …