User profiles for Claude K. Yinda

Claude Kwe Yinda

NIAID/NIH
Verified email at nih.gov
Cited by 5259

Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces viral shedding after SARS-CoV-2 D614G challenge in preclinical models

…, T Bushmaker, A Carmody, JR Port, CK Yinda… - Science translational …, 2021 - science.org
ChAdOx1 nCoV-19/AZD1222 is an approved adenovirus-based vaccine for severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) currently being deployed globally. Previous …

[HTML][HTML] Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces shedding of SARS-CoV-2 D614G in rhesus macaques

…, T Bushmaker, A Carmody, JR Port, CK Yinda… - BioRxiv, 2021 - ncbi.nlm.nih.gov
Intramuscular vaccination with ChAdOx1 nCoV-19/AZD1222 protected rhesus macaques
against pneumonia but did not reduce shedding of SARS-CoV-2. Here we investigate whether …

Viral gut metagenomics of sympatric wild and domestic canids, and monitoring of viruses: Insights from an endangered wolf population

…, R Godinho, F Álvares, CK Yinda… - Ecology and …, 2017 - Wiley Online Library
Animal host–microbe interactions are a relevant concern for wildlife conservation, particularly
regarding generalist pathogens, where domestic host species can play a role in the …

[HTML][HTML] SARS-CoV-2 infection and persistence in the human body and brain at autopsy

…, CK Yinda, CW Winkler, J Sun, JM Dickey, K Ylaya… - Nature, 2022 - nature.com
Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction 1 , 2 – 3
during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), …

[HTML][HTML] Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

…, J Schulz, N Van Doremalen, I Leighton, CK Yinda… - Nature, 2020 - nature.com
Effective therapies to treat coronavirus disease 2019 (COVID-19) are urgently needed. While
many investigational, approved, and repurposed drugs have been suggested as potential …

[HTML][HTML] Surface‒aerosol stability and pathogenicity of diverse Middle East respiratory syndrome coronavirus strains, 2012‒2018

…, T Bushmaker, J Schulz, CK Yinda… - Emerging infectious …, 2021 - ncbi.nlm.nih.gov
Middle East respiratory syndrome coronavirus (MERS-CoV) infects humans and dromedary
camels and is responsible for an ongoing outbreak of severe respiratory illness in humans in …

Persistence of SARS-CoV-2 in water and wastewater

A Bivins, J Greaves, R Fischer, KC Yinda… - … & Technology Letters, 2020 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA is frequently detected
in the feces of infected individuals. While infectious SARS-CoV-2 has not previously been …

[HTML][HTML] Ecology, evolution and spillover of coronaviruses from bats

…, T Lunn, A Morris, CE Snedden, CK Yinda… - Nature Reviews …, 2022 - nature.com
In the past two decades, three coronaviruses with ancestral origins in bats have emerged
and caused widespread outbreaks in humans, including severe acute respiratory syndrome …

Complete genome analyses of the first porcine rotavirus group H identified from a South African pig does not provide evidence for recent interspecies transmission …

…, CA Potgieter, LM Seheri, NA Page, CK Yinda… - Infection, Genetics and …, 2016 - Elsevier
Rotaviruses (RVs) are classified into eight species/groups (RVA–RVH) according to the
migration patterns of their 11 genome segments, as well as by serological and molecular …

Mechanistic theory predicts the effects of temperature and humidity on inactivation of SARS-CoV-2 and other enveloped viruses

DH Morris, KC Yinda, A Gamble, FW Rossine, Q Huang… - Elife, 2021 - elifesciences.org
Ambient temperature and humidity strongly affect inactivation rates of enveloped viruses,
but a mechanistic, quantitative theory of these effects has been elusive. We measure the …