Resolving the full spectrum of human genome variation using Linked-Reads
…, R Bharadwaj, K Bjornson, C Catalanotti… - Genome …, 2019 - genome.cshlp.org
Large-scale population analyses coupled with advances in technology have demonstrated
that the human genome is more diverse than originally thought. To date, this diversity has …
that the human genome is more diverse than originally thought. To date, this diversity has …
[HTML][HTML] Fermentation metabolism and its evolution in algae
C Catalanotti, W Yang, MC Posewitz… - Frontiers in plant …, 2013 - frontiersin.org
Fermentation or anoxic metabolism allows unicellular organisms to colonize environments
that become anoxic. Free-living unicellular algae capable of a photoautotrophic lifestyle can …
that become anoxic. Free-living unicellular algae capable of a photoautotrophic lifestyle can …
Multiple facets of anoxic metabolism and hydrogen production in the unicellular green alga Chlamydomonas reinhardtii
AR Grossman, C Catalanotti, W Yang, A Dubini… - New …, 2011 - Wiley Online Library
Many microbes in the soil environment experience micro‐oxic or anoxic conditions for much
of the late afternoon and night, which inhibit or prevent respiratory metabolism. To sustain …
of the late afternoon and night, which inhibit or prevent respiratory metabolism. To sustain …
Joint single cell DNA-seq and RNA-seq of gastric cancer cell lines reveals rules of in vitro evolution
Cancer cell lines are not homogeneous nor are they static in their genetic state and biological
properties. Genetic, transcriptional and phenotypic diversity within cell lines contributes to …
properties. Genetic, transcriptional and phenotypic diversity within cell lines contributes to …
[HTML][HTML] Reverse genetics in Chlamydomonas: a platform for isolating insertional mutants
A method was developed to identify insertional mutants of Chlamydomonas reinhardtii
disrupted for selected target genes. The approach relies on the generation of thousands of …
disrupted for selected target genes. The approach relies on the generation of thousands of …
[HTML][HTML] Single-cell sequencing of genomic DNA resolves sub-clonal heterogeneity in a melanoma cell line
…, V Kumar, Y Yin, MG Webb, C Catalanotti… - Communications …, 2020 - nature.com
We performed shallow single-cell sequencing of genomic DNA across 1475 cells from a cell-line,
COLO829, to resolve overall complexity and clonality. This melanoma tumor-line has …
COLO829, to resolve overall complexity and clonality. This melanoma tumor-line has …
Critical role of Chlamydomonas reinhardtii ferredoxin-5 in maintaining membrane structure and dark metabolism
…, A Dubini, C Catalanotti… - Proceedings of the …, 2015 - National Acad Sciences
Photosynthetic microorganisms typically have multiple isoforms of the electron transfer
protein ferredoxin, although we know little about their exact functions. Surprisingly, a …
protein ferredoxin, although we know little about their exact functions. Surprisingly, a …
A Mutant in the ADH1 Gene of Chlamydomonas reinhardtii Elicits Metabolic Restructuring during Anaerobiosis
L Magneschi, C Catalanotti, V Subramanian… - Plant …, 2012 - academic.oup.com
The green alga Chlamydomonas reinhardtii has numerous genes encoding enzymes that
function in fermentative pathways. Among these, the bifunctional alcohol/acetaldehyde …
function in fermentative pathways. Among these, the bifunctional alcohol/acetaldehyde …
Mutagenesis and phenotypic selection as a strategy toward domestication of Chlamydomonas reinhardtii strains for improved performance in photobioreactors
…, C Formighieri, M Mantelli, C Catalanotti… - Photosynthesis …, 2011 - Springer
Microalgae have a valuable potential for biofuels production. As a matter of fact, algae can
produce different molecules with high energy content, including molecular hydrogen (H 2 ) by …
produce different molecules with high energy content, including molecular hydrogen (H 2 ) by …
Altered Fermentative Metabolism in Chlamydomonas reinhardtii Mutants Lacking Pyruvate Formate Lyase and Both Pyruvate Formate Lyase and Alcohol …
C Catalanotti, A Dubini, V Subramanian, W Yang… - The Plant …, 2012 - academic.oup.com
Chlamydomonas reinhardtii, a unicellular green alga, often experiences hypoxic/anoxic soil
conditions that activate fermentation metabolism. We isolated three Chlamydomonas …
conditions that activate fermentation metabolism. We isolated three Chlamydomonas …