A complete understanding of how exposure to environmental substances promotes cancer
formation is lacking. More than 70 years ago, tumorigenesis was proposed to occur in a two-…

Lung cancer is the leading cause of cancer-associated mortality worldwide 1 . Here we
analysed 1,644 tumour regions sampled at surgery or during follow-up from the first 421 patients …

Fluorescence lifetime imaging (FLIM) is a powerful microscopy technique for providing contrast
of biological and other systems by differences in molecular species or their environments…

INTRODUCTION G protein–coupled receptors (GPCRs) are a superfamily of seven
transmembrane-spanning receptors and are the target of 30% of all US Food and Drug …

Background: Cellular energy is required for the healing cascade to occur. A combination of
cells, cytokines, chemokines, tissue perfusion, an extracellular matrix, and local forces are …

This study provides novel insights into the spatial organization of the lung cancer TME in the
context of tumor immunogenicity, tumor heterogeneity, and cancer evolution. Pairing the …

Results FL enabled more rapid and accurate identification and localization of primary tumors
and metastases than BL. Using BL took statistically significantly longer time than FL. More …

We investigated the cell‐killing efficacy of UV light on cancer cells expressing GFP in the
nucleus and RFP in the cytoplasm (dual‐color cells). After exposure to various doses of UVA, …

Background The aim of this study was to improve fluorescence laparoscopy of pancreatic
cancer in an orthotopic mouse model with the use of a light-emitting diode (LED) light source …

Wound healing is a complex pathway that requires cells, an appropriate biochemical
environment (ie, cytokines, chemokines), an extracellular matrix, perfusion, and the application of …