User profiles for Claudia Wierzbicki

Claudia Wierzbicki

Centre for Genomic Research, University of Liverpool
Verified email at liverpool.ac.uk
Cited by 2813

Recent Asian origin of chytrid fungi causing global amphibian declines

…, R Verster, J Vörös, RJ Webb, C Wierzbicki… - Science, 2018 - science.org
Globalized infectious diseases are causing species declines worldwide, but their source often
remains elusive. We used whole-genome sequencing to solve the spatiotemporal origins …

[PDF][PDF] Generation and transmission of interlineage recombinants in the SARS-CoV-2 pandemic

…, F Todd, HJ Webster, M Whitehead, C Wierzbicki… - Cell, 2021 - cell.com
We present evidence for multiple independent origins of recombinant SARS-CoV-2 viruses
sampled from late 2020 and early 2021 in the United Kingdom. Their genomes carry single-…

[HTML][HTML] In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains

…, G Ozhan-Kizil, A Mongera, D Beis, C Wierzbicki… - Developmental …, 2012 - Elsevier
The creation of molecular tools able to unravel in vivo spatiotemporal activation of specific
cell signaling events during cell migration, differentiation and morphogenesis is of great …

[HTML][HTML] Chytrid fungus infection in zebrafish demonstrates that the pathogen can parasitize non-amphibian vertebrate hosts

N Liew, MJ Mazon Moya, CJ Wierzbicki… - Nature …, 2017 - nature.com
Aquatic chytrid fungi threaten amphibian biodiversity worldwide owing to their ability to
rapidly expand their geographical distributions and to infect a wide range of hosts. Combating …

Antagonism between Gdf6a and retinoic acid pathways controls timing of retinal neurogenesis and growth of the eye in zebrafish

LE Valdivia, DB Lamb, W Horner, C Wierzbicki… - …, 2016 - journals.biologists.com
Maintaining neurogenesis in growing tissues requires a tight balance between progenitor cell
proliferation and differentiation. In the zebrafish retina, neuronal differentiation proceeds in …

Post‐epizootic microbiome associations across communities of neotropical amphibians

P Jervis, P Pintanel, K Hopkins, C Wierzbicki… - Molecular …, 2021 - Wiley Online Library
Microbiome–pathogen interactions are increasingly recognized as an important element of
host immunity. While these host‐level interactions will have consequences for community …

[HTML][HTML] Development and worldwide use of non-lethal, and minimal population-level impact, protocols for the isolation of amphibian chytrid fungi

…, JMG Shelton, K Bates, L Brookes, C Wierzbicki… - Scientific reports, 2018 - nature.com
Parasitic chytrid fungi have emerged as a significant threat to amphibian species worldwide,
necessitating the development of techniques to isolate these pathogens into culture for …

Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification

…, HL Stickney, Q Schwarz, LM Lawrence, C Wierzbicki… - Elife, 2019 - elifesciences.org
10.7554/eLife.40093.001 The vertebrate eye originates from the eye field, a domain of cells
specified by a small number of transcription factors. In this study, we show that Tcf7l1a is one …

Climate structuring of Batrachochytrium dendrobatidis infection in the threatened amphibians of the northern Western Ghats, India

…, MC Fisher, CJ Wierzbicki… - Royal Society …, 2018 - royalsocietypublishing.org
Batrachochytrium dendrobatidis (Bd) is a pathogen killing amphibians worldwide. Its impact
across much of Asia is poorly characterized. This study systematically surveyed amphibians …

[HTML][HTML] Microbiome function predicts amphibian chytridiomycosis disease dynamics

…, U Sommer, KP Hopkins, JMG Shelton, C Wierzbicki… - Microbiome, 2022 - Springer
Background The fungal pathogen Batrachochytrium dendrobatidis (Bd) threatens amphibian
biodiversity and ecosystem stability worldwide. Amphibian skin microbial community …