In the past decade, the potential of harnessing the ability of nuclear magnetic resonance (NMR)
spectroscopy to monitor intermolecular interactions as a tool for drug discovery has been …

… Author links open overlay panel Ivano Bertini a , Claudio Luchinat b , Giacomo Parigi b …

This article deals with the solution structure determination of paramagnetic metalloproteins
by NMR spectroscopy. These proteins were believed not to be suitable for NMR …

… Koenig at a later stage was important for both Ivano Bertini and Claudio Luchinat. A special
role in our understanding of the intricacies of paramagnetic shifts and relaxation has been …

H NMR metabolic profiling of urine, serum and plasma has been used to monitor the impact
of the pre-analytical steps on the sample quality and stability in order to propose standard …

The amyloid fibrils of beta-amyloid (Aβ) peptides play important roles in the pathology of
Alzheimer’s disease. Comprehensive solid-state NMR (SSNMR) structural studies on uniformly …

In the Spring of 2013, NMR spectroscopists convened at the Weizmann Institute in Israel to
brainstorm on approaches to improve the sensitivity of NMR experiments, particularly when …

Many diseases cause significant changes to the concentrations of small molecules (aka
metabolites) that appear in a person’s biofluids, which means such diseases can often be …

Metabolomics deals with the whole ensemble of metabolites (the metabolome). As one of the
‐omic sciences, it relates to biology, physiology, pathology and medicine; but metabolites …

The study of metabolic responses to drugs, environmental changes, and diseases is a new
promising area of metabonomic research. Metabolic fingerprints can be obtained by …