User profiles for Clemens A van Blitterswijk

Clemens A van Blitterswijk

Maastricht University
Verified email at maastrichtuniversity.nl
Cited by 58315

Vascularization in tissue engineering

J Rouwkema, NC Rivron, CA van Blitterswijk - Trends in biotechnology, 2008 - cell.com
Tissue engineering has been an active field of research for several decades now. However,
the amount of clinical applications in the field of tissue engineering is still limited. One of the …

Bone regeneration: molecular and cellular interactions with calcium phosphate ceramics

F Barrère, CA van Blitterswijk… - International journal of …, 2006 - Taylor & Francis
Calcium phosphate bioceramics are widely used in orthopedic and dental applications and
porous scaffolds made of them are serious candidates in the field of bone tissue engineering…

[PDF][PDF] Osteoinductive biomaterials: current knowledge of properties, experimental models and biological mechanisms

AM Barradas, H Yuan, CA van Blitterswijk… - Eur Cell Mater, 2011 - ris.utwente.nl
In the past thirty years, a number of biomaterials have shown the ability to induce bone
formation when implanted at heterotopic sites, an ability known as osteoinduction. Such …

Engineering vascularized skeletal muscle tissue

…, DC Darland, R Marini, CA Van Blitterswijk… - Nature …, 2005 - nature.com
One of the major obstacles in engineering thick, complex tissues such as muscle is the need
to vascularize the tissue in vitro. Vascularization in vitro could maintain cell viability during …

Osteoinductive ceramics as a synthetic alternative to autologous bone grafting

…, WR Walsh, CA Van Blitterswijk… - Proceedings of the …, 2010 - National Acad Sciences
Biomaterials can be endowed with biologically instructive properties by changing basic
parameters such as elasticity and surface texture. However, translation from in vitro proof of …

3D microenvironment as essential element for osteoinduction by biomaterials

…, CM Van Der Valk, G Meijer, CA van Blitterswijk… - Biomaterials, 2005 - Elsevier
In order to unravel the mechanism of osteoinduction by biomaterials, in this study we
investigated the influence of the specific surface area on osteoinductive properties of two types of …

Design of porous scaffolds for cartilage tissue engineering using a three-dimensional fiber-deposition technique

…, J De Wijn, F Peters, J Riesle, CA van Blitterswijk - Biomaterials, 2004 - Elsevier
In this study, we present and characterize a fiber deposition technique for producing three-dimensional
poly(ethylene glycol)-terephthalate—poly(butylene terephthalate) (PEGT/PBT) …

Biomimetic hydroxyapatite coating on metal implants

…, F Barrere, CA Van Blitterswijk… - Journal of the …, 2002 - Wiley Online Library
The combination of the high mechanical strength of metals with the osteoconductive properties
of calcium phosphates make hydroxyapatite coatings on titanium implants widely used in …

Enzyme-catalyzed crosslinkable hydrogels: emerging strategies for tissue engineering

LSM Teixeira, J Feijen, CA van Blitterswijk, PJ Dijkstra… - Biomaterials, 2012 - Elsevier
State-of-the-art bioactive hydrogels can easily and efficiently be formed by enzyme-catalyzed
mild-crosslinking reactions in situ. Yet this cell-friendly and substrate-specific method …

Osteoinduction by biomaterials—physicochemical and structural influences

…, MA van den Doel, CA van Blitterswijk… - … Research Part A: An …, 2006 - Wiley Online Library
Osteoinduction by biomaterials has been shown to be a real phenomenon by many investigators
in the last decade. The exact mechanism of this phenomenon is, however, still largely …