Background & Aims 24-NorUrsodeoxycholic acid (NorUDCA) is a novel therapeutic bile
acid for immune-mediated cholestatic liver diseases, such as primary sclerosing cholangitis (…

The spatial and temporal organization of T cell signaling molecules is increasingly accepted
as a crucial step in controlling T cell activation. CD222, also known as the cation-…

The plasminogen (Plg) activation cascade on the cell surface plays a central role in cell
migration and is involved in a plethora of physiological and pathological processes. Its …

Interstitial lung disease comprises numerous clinical entities posing significant challenges
towards a prompt and accurate diagnosis. Amongst the contributing factors are intricate …

The plasminogen system is harnessed in a wide variety of physiological processes, such as
fibrinolysis, cell migration, or efferocytosis; and accordingly, it is essential upon inflammation…

Background Oral cholera vaccines consisting of killed whole cells have been available for
many years, but they have not been used extensively in populations with endemic disease. An …

Background Typhoid fever remains an important cause of illness and death in the developing
world. Uncertainties about the protective effect of Vi polysaccharide vaccine in children …

Background Efficacy and safety of a two-dose regimen of bivalent killed whole-cell oral
cholera vaccine (Shantha Biotechnics, Hyderabad, India) to 3 years is established, but long-term …

Background Killed oral cholera vaccines (OCVs) have been licensed for use in developing
countries, but protection conferred by licensed OCVs beyond two years of follow-up has not …

Background. We evaluated the herd protection conferred by an oral cholera vaccine using 2
approaches: cluster design and geographic information system (GIS) design. Methods. …