User profiles for Colette L. Picard

Colette L Picard

Postdoc, UCLA
Verified email at ucla.edu
Cited by 940

[HTML][HTML] RNA-directed DNA methylation

RM Erdmann, CL Picard - PLoS genetics, 2020 - journals.plos.org
RNA-directed DNA methylation (RdDM) is a biological process in which non-coding RNA
molecules direct the addition of DNA methylation to specific DNA sequences. The RdDM …

Natural epigenetic polymorphisms lead to intraspecific variation in Arabidopsis gene imprinting

D Pignatta, RM Erdmann, E Scheer, CL Picard… - Elife, 2014 - elifesciences.org
10.7554/eLife.03198.001 Imprinted gene expression occurs during seed development in
plants and is associated with differential DNA methylation of parental alleles, particularly at …

Transcriptional and imprinting complexity in Arabidopsis seeds at single-nucleus resolution

CL Picard, RA Povilus, BP Williams, M Gehring - Nature plants, 2021 - nature.com
Seeds are a key life cycle stage for many plants. Seeds are also the basis of agriculture and
the primary source of calories consumed by humans 1 . Here, we employ single-nucleus …

Conserved imprinting associated with unique epigenetic signatures in the Arabidopsis genus

M Klosinska, CL Picard, M Gehring - Nature Plants, 2016 - nature.com
In plants, imprinted gene expression occurs in endosperm seed tissue and is sometimes
associated with differential DNA methylation between maternal and paternal alleles 1. …

[HTML][HTML] The histone variant H2A. W and linker histone H1 co-regulate heterochromatin accessibility and DNA methylation

P Bourguet, CL Picard, R Yelagandula… - Nature …, 2021 - nature.com
In flowering plants, heterochromatin is demarcated by the histone variant H2A.W, elevated
levels of the linker histone H1, and specific epigenetic modifications, such as high levels of …

[PDF][PDF] Single-nucleus RNA-seq reveals that MBD5, MBD6, and SILENZIO maintain silencing in the vegetative cell of developing pollen

L Ichino, CL Picard, J Yun, M Chotai, S Wang, EK Lin… - Cell reports, 2022 - cell.com
Silencing of transposable elements (TEs) drives the evolution of numerous redundant
mechanisms of transcriptional regulation. Arabidopsis MBD5, MBD6, and SILENZIO act as TE …

CRISPR-based targeting of DNA methylation in Arabidopsis thaliana by a bacterial CG-specific DNA methyltransferase

B Ghoshal, CL Picard, B Vong… - Proceedings of the …, 2021 - National Acad Sciences
CRISPR-based targeted modification of epigenetic marks such as DNA cytosine methylation
is an important strategy to regulate the expression of genes and their associated …

[HTML][HTML] A viral guide RNA delivery system for CRISPR-based transcriptional activation and heritable targeted DNA demethylation in Arabidopsis thaliana

B Ghoshal, B Vong, CL Picard, S Feng, JM Tam… - PLoS …, 2020 - journals.plos.org
Plant RNA viruses are used as delivery vectors for their high level of accumulation and
efficient spread during virus multiplication and movement. Utilizing this concept, several viral-…

The role of ATXR6 expression in modulating genome stability and transposable element repression in Arabidopsis

ME Potok, Z Zhong, CL Picard, Q Liu… - Proceedings of the …, 2022 - National Acad Sciences
ARABIDOPSIS TRITHORAX-RELATED PROTEIN 5 (ATXR5) AND ATXR6 are required for
the deposition of H3K27me1 and for maintaining genomic stability in Arabidopsis. Reduction …

[HTML][HTML] Proximal methylation features associated with nonrandom changes in gene body methylation

CL Picard, M Gehring - Genome Biology, 2017 - Springer
Background Gene body methylation at CG dinucleotides is a widely conserved feature of
methylated genomes but remains poorly understood. The Arabidopsis thaliana strain Cvi has …