This report is the first complete assessment of the science of climate change since Working
Group I (WGI) of the IPCC produced its second report Climate Change 1995: The Science of …

Background and objective The Atlanta classification of acute pancreatitis enabled
standardised reporting of research and aided communication between clinicians. Deficiencies …

Cytosine residues in the sequence 5′CpG (cytosine–guanine) are often postsynthetically
methylated in animal genomes. CpG methylation is involved in long-term silencing of certain …

Pancreatic cancer is a major cause of cancer-associated mortality, with a dismal overall
prognosis that has remained virtually unchanged for many decades. Currently, prevention or …

Objective —To estimate the annual cost of infections attributable to porcine reproductive and
respiratory syndrome (PRRS) virus to US swine producers. Design —Economic analysis. …

Mammalian DNA is methylated at many CpG dinucleotides. The biological consequences of
methylation are mediated by a family of methyl-CpG binding proteins 1, 2, 3, 4. The best …

Fibrotic rigidification following a myocardial infarct is known to impair cardiac output, and it
is also known that cardiomyocytes on rigid culture substrates show a progressive loss of …

We document the development of the first version of the UK Earth System Model UKESM1.
The model represents a major advance on its predecessor HadGEM2‐ES, with …

BACKGROUND: Patients with stomas face many difficulties both physical and psychological.
Little is known about the long-term problems and the impact on patient lifestyle of a …

Neurodegenerative disorders with high brain iron include Parkinson disease, Alzheimer
disease and several childhood genetic disorders categorized as neuroaxonal dystrophies. We …