Massively multiplexed affinity characterization of therapeutic antibodies against SARS-CoV-2 variants
Antibody therapies represent a valuable tool to reduce COVID-19 deaths and hospitalizations.
Multiple antibody candidates have been granted emergency use authorization by the …
Multiple antibody candidates have been granted emergency use authorization by the …
Neuron-astrocyte networking: astrocytes orchestrate and respond to changes in neuronal network activity across brain states and behaviors
MR Van Horn, NJ Benfey, C Shikany… - Journal of …, 2021 - journals.physiology.org
Astrocytes are known to play many important roles in brain function. However, research
underscoring the extent to which astrocytes modulate neuronal activity is still underway. Here we …
underscoring the extent to which astrocytes modulate neuronal activity is still underway. Here we …
High-throughput ML-guided design of diverse single-domain antibodies against SARS-CoV-2
…, R Emerson, B Alipanahi, C Lin, C Shikany… - bioRxiv, 2023 - biorxiv.org
Treating rapidly evolving pathogenic diseases such as COVID-19 requires a therapeutic
approach that accommodates the emergence of viral variants over time. Our machine learning (…
approach that accommodates the emergence of viral variants over time. Our machine learning (…
Selective IL-21 and IFN-alpha immunocytokines engineered using the AlphaSeq platform
C Lin, C Shikany, L Homad, J Fint, R Bansal… - Cancer Research, 2024 - AACR
Although cytokine therapies have demonstrated curative effects in some cancer patients,
clinical use remains limited due to undesired toxicity profiles accompanying systemic …
clinical use remains limited due to undesired toxicity profiles accompanying systemic …
High-throughput ML-guided design of diverse single-domain antibodies against SARS-CoV-2 (preprint)
…, R Emerson, B Alipanahi, C Lin, C Shikany… - 2023 - pesquisa.bvsalud.org
Treating rapidly evolving pathogenic diseases such as COVID-19 requires a therapeutic
approach that accommodates the emergence of viral variants over time. Our machine learning (…
approach that accommodates the emergence of viral variants over time. Our machine learning (…
Massively Multiplexed Affinity Characterization of Therapeutic Antibodies Against SARS-CoV-2 Variants (preprint)
Antibody therapies represent a valuable tool to reduce COVID-19 deaths and hospitalizations.
Multiple antibody candidates have been granted emergency use authorization by the FDA …
Multiple antibody candidates have been granted emergency use authorization by the FDA …
[PDF][PDF] Good News
F Blaney - People, 1992 - crossworks.holycross.edu
… Alfred Shikany Joe & Colleen Shikany Joseph & Joyce Shikany Suzanne Shikany Larry
Tanber Mary Wendt Carl, Nora & Paul Werner M/M John Wienke Bill & Lil Yeater …
Tanber Mary Wendt Carl, Nora & Paul Werner M/M John Wienke Bill & Lil Yeater …
[HTML][HTML] Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration
…, JI Rotter, PJ Schreiner, J Shikany… - Nature …, 2019 - nature.com
Both short and long sleep are associated with an adverse lipid profile, likely through different
biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we …
biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we …
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci
…, BL Salako, PJ Schreiner, JM Shikany… - Molecular …, 2021 - nature.com
Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low
SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci, …
SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci, …
Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep …
…, T Roenneberg, JI Rotter, PJ Schreiner, J Shikany… - bioRxiv, 2019 - biorxiv.org
Both short and long sleep are associated with an adverse lipid profile, likely through different
biological pathways. To provide new insights in the biology of sleep-associated adverse …
biological pathways. To provide new insights in the biology of sleep-associated adverse …