User profiles for Colwyn Headley
Colwyn A. HeadleyStanford University, Texas Biomedical Research Institute Verified email at stanford.edu Cited by 483 |
[HTML][HTML] Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice
Vaccine and antiviral development against SARS-CoV-2 infection or COVID-19 disease
would benefit from validated small animal models. Here, we show that transgenic mice …
would benefit from validated small animal models. Here, we show that transgenic mice …
[HTML][HTML] Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target
…, MG Levin, JM Spin, YH Rhee, A Deng, CA Headley… - Nature …, 2023 - nature.com
Abdominal aortic aneurysm (AAA) is a common disease with substantial heritability. In this
study, we performed a genome-wide association meta-analysis from 14 discovery cohorts and …
study, we performed a genome-wide association meta-analysis from 14 discovery cohorts and …
[HTML][HTML] Building the case for mitochondrial transplantation as an anti-aging cardiovascular therapy
CA Headley, PS Tsao - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
Mitochondrial dysfunction is a common denominator in both biological aging and cardiovascular
disease pathology. Understanding the protagonist role of mitochondria in the respective …
disease pathology. Understanding the protagonist role of mitochondria in the respective …
Diversity, equity and inclusion in the laboratory: strategies to enhance inclusive laboratory culture
Building a diverse laboratory that is equitable is critical for the retention of talent and the
growth of trainees professionally and personally. Here, we outline several strategies including …
growth of trainees professionally and personally. Here, we outline several strategies including …
Similarities and differences between porcine mandibular and limb bone marrow mesenchymal stem cells
Objective Research has shown promise of using bone marrow mesenchymal stem cells (BMSCs)
for craniofacial bone regeneration; yet little is known about the differences of BMSCs …
for craniofacial bone regeneration; yet little is known about the differences of BMSCs …
A practical guide to graduate school interviewing for historically excluded individuals
…, P Rodriguez-Aliaga, CA Headley… - American Journal …, 2023 - journals.physiology.org
Completing graduate school applications can be a challenging process but navigating
subsequent 50 graduate school interviews can be just as difficult. Historically excluded students …
subsequent 50 graduate school interviews can be just as difficult. Historically excluded students …
Multi-ancestry GWAS deciphers genetic architecture of abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target
…, MG Levin, JM Spin, YH Rhee, A Deng, CA Headley… - Medrxiv, 2022 - medrxiv.org
Abdominal aortic aneurysm (AAA) is a common disease with significant heritability. In this
study, we performed a genome-wide association meta-analysis from 14 discovery cohorts and …
study, we performed a genome-wide association meta-analysis from 14 discovery cohorts and …
IL-10 Receptor blockade delivered simultaneously with Bacillus calmette–guérin vaccination sustains long-term protection against Mycobacterium tuberculosis …
Mycobacterium bovis bacillus Calmette–Guérin (BCG) immunization still remains the best
vaccination strategy available to control the development of active tuberculosis. Protection …
vaccination strategy available to control the development of active tuberculosis. Protection …
[HTML][HTML] Unlocking the power of virtual networking for early-career researchers
CA Hayes, JT Moore, CA Headley, AL Berrios-Negron… - Elife, 2024 - elifesciences.org
Many successful researchers in the biomedical sciences have benefitted from mentors and
networks earlier in their career. However, early-career researchers from minoritized and …
networks earlier in their career. However, early-career researchers from minoritized and …
Nontuberculous mycobacterium M. avium infection predisposes aged mice to cardiac abnormalities and inflammation
CA Headley, A Gerberick, S Mehta, Q Wu, L Yu… - Aging …, 2019 - Wiley Online Library
Biological aging dynamically alters normal immune and cardiac function, favoring the
production of pro‐inflammatory cytokines (IL‐1β, IL‐6, and TNF‐α) and increased instances of …
production of pro‐inflammatory cytokines (IL‐1β, IL‐6, and TNF‐α) and increased instances of …