Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2, has spread globally, and no proven treatments are available. Convalescent plasma …

Group A Streptococcus (GAS) causes human infections that range in severity from pharyngitis
("strep-throat") to necrotizing fasciitis ("flesh-eating disease"). To facilitate investigation of …

Streptococcus pyogenes causes 700 million human infections annually worldwide, yet, despite
a century of intensive effort, there is no licensed vaccine against this bacterium. Although …

Group A Streptococcus (GAS) causes an exceptionally broad range of infections in humans,
from relatively mild pharyngitis and skin infections to life-threatening necrotizing fasciitis and …

Background COVID-19 disease, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), has spread globally, and no proven treatments are available. Convalescent …

Next-generation sequencing technology is available to many clinical laboratories; however,
it is not yet widely used in routine microbiology practice. To demonstrate the feasibility of …

Necrotizing fasciitis and myositis are devastating infections characterized by high mortality.
Group A streptococcus (GAS) is a common cause of these infections, but the molecular …

A fundamental goal of contemporary biomedical research is to understand the molecular
basis of disease pathogenesis and exploit this information to develop targeted and more-…

Streptococcus agalactiae (group B streptococcus [GBS]) is a major cause of infections in
newborns, pregnant women, and immunocompromised patients. GBS strain CNCTC10/84 is a …

Group A streptococcus (GAS) is a major pathogen that impacts health and economic affairs
worldwide. Although the oropharynx is the primary site of infection, GAS can colonize the …