MicroRNA (miRNA) deregulation plays a critical role in tumorigenesis. miR-23b and miR-130b
are induced by thyrotropin in thyroid cells in a cAMP-dependent manner. The aim of our …

Congenital Dyserythropoietic Anemia II (CDA II) is a rare hyporegenerative anemia of
variable degree, whose causative gene is SEC23B. More than 60 causative mutations in 142 …

Congenital erythropoietic porphyria ( CEP ) is a rare genetic disease that is characterized by
a severe cutaneous photosensitivity causing unrecoverable deformities, chronic hemolytic …

Congenital dyserythropoietic anemia type II, a recessive disorder of erythroid differentiation,
is due to mutations in SEC23B, a component of the core trafficking machinery COPII. In no …

… Vincenza Leone, 1 Concetta Langella, 1 Francesco Esposito, 1 Claudio Arra, 2 Giuseppe
Palma, 2 Domenica Rea, 2 Orlando Paciello, 3 Francesco Merolla, 1 Davide De Biase, 3 …

CDA are a group of inherited, rare diseases that are characterized by dyserythropoiesis and
ineffective erythropoiesis associated with transfusion dependency in approximately 10% of …

Neuroblastoma (NBL) accounts for >7% of malignancies in patients younger than 15 years.
Low- and intermediate-risk patients exhibit excellent or good prognosis after treatment, …

Background Transposable elements (TEs) widely contribute to the evolution of genomes
allowing genomic innovations, generating germinal and somatic heterogeneity, and giving birth …

We have previously studied the function of microRNAs (miRNAs) in thyroid cells using the
differentiated rat thyroid PC Cl 3 cells that need thyrotropin (TSH) for their growth. The miRNA …

We have previously reported that the expression of the CL2/CCDC80 gene is downregulated
in human papillary thyroid carcinomas, particularly in follicular variants. We have also …