User profiles for Connar Stanley James Westgate

Connar Westgate

Danish Headache Centre
Verified email at bham.ac.uk
Cited by 755

[HTML][HTML] Long-term monitoring of intracranial pressure in freely-moving rats; impact of different physiological states

S Eftekhari, CSJ Westgate, KP Johansen… - Fluids and Barriers of …, 2020 - Springer
Background Elevated intracranial pressure (ICP) is observed in association with a range of
brain disorders. There is limited insight into the regulatory mechanisms of ICP under …

[HTML][HTML] Understanding the link between obesity and headache-with focus on migraine and idiopathic intracranial hypertension

CSJ Westgate, IME Israelsen, RH Jensen… - The journal of headache …, 2021 - Springer
Background Obesity confers adverse effects to every system in the body including the
central nervous system. Obesity is associated with both migraine and idiopathic intracranial …

[HTML][HTML] The impact of obesity-related raised intracranial pressure in rodents

CSJ Westgate, SM Hagen, IME Israelsen, S Hamann… - Scientific Reports, 2022 - nature.com
Elevated intracranial pressure (ICP) is observed in many brain disorders. Obesity has been
linked to ICP pathogenesis in disorders such as idiopathic intracranial pressure (IIH). We …

[HTML][HTML] Preclinical update on regulation of intracranial pressure in relation to idiopathic intracranial hypertension

S Eftekhari, CSJ Westgate, MS Uldall… - Fluids and Barriers of the …, 2019 - Springer
Background Elevated intracranial pressure (ICP) is observed in association with a range of
brain disorders. One of these challenging disorders is idiopathic intracranial hypertension (IIH…

Effects of caffeine on intracranial pressure and pain perception in freely moving rats

IME Israelsen, CSJ Westgate… - … : The Journal of …, 2023 - Wiley Online Library
Objective Caffeine, a non‐selective adenosine receptor (AR) antagonist, is the most consumed
psychostimulant in the world. Caffeine has been suggested to regulate cerebrospinal …

[HTML][HTML] Glucocorticoids modify intracranial pressure in freely moving rats

CSJ Westgate, IME Israelsen, C Kamp-Jensen… - Fluids and Barriers of …, 2023 - Springer
Background Glucocorticoids (GCs) are widely prescribed for a variety of inflammatory
diseases, but they are also used to treat raised intracranial pressure (ICP) caused by trauma or …

Acetazolamide and topiramate lower intracranial pressure through differential mechanisms: The effect of acute and chronic administration

CSJ Westgate, C Kamp‐Jensen… - British Journal of …, 2024 - Wiley Online Library
Background and Purpose Diseases of raised intracranial pressure (ICP) cause severe
morbidity and mortality. Multiple drugs are utilised to lower ICP including acetazolamide and …

[HTML][HTML] Exposure to topiramate and acetazolamide causes endocrine disrupting effects in female rats during estrus

…, B Styrishave, RH Jensen, CSJ Westgate - Toxicology and Applied …, 2024 - Elsevier
Background Idiopathic intracranial hypertension (IIH) is a disease characterized by elevated
intracranial pressure (ICP) and is a disease of young females. The first line pharmacological …

[HTML][HTML] Cycle-dependent sex differences in expression of membrane proteins involved in cerebrospinal fluid secretion at rat choroid plexus

IME Israelsen, C Kamp-Jensen, CSJ Westgate… - BMC neuroscience, 2023 - Springer
Background Female sex is a known risk factor of brain disorders with raised intracranial
pressure (ICP) and sex hormones have been suggested to alter cerebrospinal fluid (CSF) …

Translational modeling of non-traumatic raised intracranial pressure in rodents; the impact of diet-induced obesity on cephalic hypersensitivity and retinal …

CSJ Westgate, SM Hagen, IME Israelsen, S Hamann… - bioRxiv, 2021 - biorxiv.org
Elevated intracranial pressure (ICP) is a feature of critical cerebral disorders. Obesity has
been linked to raised ICP, and especially to disorders such as idiopathic intracranial pressure (…