Injectable, biodegradable scaffolds are important biomaterials for tissue engineering and
drug delivery. Hydrogels derived from natural polysaccharides are ideal scaffolds as they …

Articular cartilage injury and degeneration are leading causes of disability. Animal studies
are critically important to developing effective treatments for cartilage injuries. This review …

Efforts to expand treatment options for articular cartilage repair have increasingly focused
on the implantation of cell‐polymer constructs. The purpose of this study is to determine the …

Objective: To test the hypothesis that platelet-rich fibrin glue (PR-FG) can be used clinically
as a scaffold to deliver autologous culture-expanded bone marrow mesenchymal stem cells (…

Between December 1983 and August 1991, 55 consecutive patients (55 knees) who
underwent articular cartilage transplantation to their damaged knees were enrolled in the study. …

Objectives While various monocyte chemokine systems are increased in expression in
osteoarthritis (OA), the hierarchy of chemokines and chemokine receptors in mediating monocyte/…

Background: The effect of platelet-rich plasma (PRP) on chondrocytes has been studied in
cell and tissue culture, but considerably less attention has been given to the effect of PRP on …

The anterior cruciate ligament (ACL) a relatively common injury in young, physically active
individuals. ACL injuries are seen at high incidence in adolescents playing sports that involve …

Osteoarthritis is a prevalent and disabling disease affecting an increasingly large swathe of
the world population. While clinical osteoarthritis is a late-stage condition for which disease-…

Purpose: Intra-articular use of 0.5% bupivacaine is common in arthroscopic surgery. This
study was conducted to test the hypotheses that (1) 0.5% bupivacaine is toxic to articular …