Simultaneous quantification of protein–DNA contacts and transcriptomes in single cells

K Rooijers, CM Markodimitraki, FJ Rang… - Nature …, 2019 - nature.com
Protein–DNA interactions are critical to the regulation of gene expression, but it remains
challenging to define how cell-to-cell heterogeneity in protein–DNA binding influences gene …

Simultaneous quantification of protein–DNA interactions and transcriptomes in single cells with scDam&T-seq

CM Markodimitraki, FJ Rang, K Rooijers, SS de Vries… - Nature protocols, 2020 - nature.com
Protein–DNA interactions are essential for establishing cell type–specific chromatin architecture
and gene expression. We recently developed scDam&T-seq, a multi-omics method that …

[HTML][HTML] scDam&T‐seq combines DNA adenine methyltransferase-based labeling of protein-DNA contact sites with transcriptome sequencing to analyze regulatory …

K Rooijers, CM Markodimitraki, FJ Rang… - Nature …, 2019 - ncbi.nlm.nih.gov
Protein-DNA interactions are critical to the regulation of gene expression, but it remains
challenging to define how cell-to-cell heterogeneity in protein-DNA binding influences gene …

A tale of two measurements: protein-DNA interactions and gene expression in single cells. Protein-DNA interactions and gene expression in single cells

CM Markodimitraki - 2020 - pure.knaw.nl
Our bodies are composed of trillions of cells which are the building blocks that cooperate
with each other. A neuron has a characteristic tree-like appearance and is specialized in …

From stem cells to neurons: epigenetic mechanisms governing neurogenesis.

CM Markodimitraki - 2014 - studenttheses.uu.nl
The development of one of the most important systems of the human body, the nervous
system, is definitely a very complicated and less understood process. The nervous system …

[HTML][HTML] Catching global interactions in vivo

Y Qiu, S Huang - Cell & Bioscience, 2017 - Springer
Histone proteins and transcription factors (TFs) play critical roles in gene transcription and
development of multicellular organisms. Although antibody mediated protein isolation couple …

[PDF][PDF] Induced quiescence of Lgr5+ stem cells in intestinal organoids enables differentiation of hormone-producing enteroendocrine cells

O Basak, J Beumer, K Wiebrands, H Seno… - Cell stem cell, 2017 - cell.com
… We thank Kim Boonekamp and Corina Markodimitraki for critical reading of the manuscript.
HC is listed as the inventor on several patents related to this work. This work was supported …

[HTML][HTML] Chromatin profiling techniques: exploring the chromatin environment and its contributions to complex traits

A Chawla, C Nagy, G Turecki - International Journal of Molecular …, 2021 - mdpi.com
The genetic architecture of complex traits is multifactorial. Genome-wide association studies
(GWASs) have identified risk loci for complex traits and diseases that are disproportionately …

[BOOK][B] The Relation Between Drought Impacts, Drought Indicators, Water Scarcity and Aridity:: The Case of Kenya

M Lam - 2022 - edepot.wur.nl
… Thanks to Corina Markodimitraki, who gave me a very warm welcome in the 510 team
and who I could always contact to connect me to any vol- 860 unteer of the organization. …

Taking language samples home: Feasibility, reliability, and validity of child language samples conducted remotely with video chat versus in-person

BL Manning, A Harpole, EM Harriott… - Journal of Speech …, 2020 - ASHA
Purpose There has been increased interest in using telepractice for involving more diverse
children in research and clinical services, as well as when in-person assessment is …