A versatile cis-acting element reporter system to study the function, maturation and stability of ribosomal RNA mutants in archaea

M Jüttner, M Weiß, N Ostheimer, C Reglin… - Nucleic Acids …, 2020 - academic.oup.com
General molecular principles of ribosome biogenesis have been well explored in bacteria and
eukaryotes. Collectively, these studies have revealed important functional differences and …

Identifying Novel Drug Targets by iDTPnd: A Case Study of Kinase Inhibitors

H Naveed, C Reglin, T Schubert, X Gao… - Genomics …, 2021 - academic.oup.com
Current FDA-approved kinase inhibitors cause diverse adverse effects, some of which are
due to the mechanism-independent effects of these drugs. Identifying these mechanism-…

Identifying novel targets by using drug-binding site signature: A case study of kinase inhibitors

H Naveed, C Reglin, T Schubert, X Gao, ST Arold… - bioRxiv, 2019 - biorxiv.org
Current FDA-approved kinase inhibitors cause diverse adverse effects, some of which are
due to the mechanism-independent effects of these drugs. Identifying these mechanism-…

[PDF][PDF] Non-radioactive In Vivo Labeling of RNA with 4-Thiouracil

C Braun, R Knüppel, J Perez-Fernandez… - Ribosome Biogenesis …, 2022 - library.oapen.org
… Karl-Dieter Entian (University of Frankfurt) for comments and suggestions, to Corinna Reglin
for early contribution to this project. We would like to thank our colleagues from the chair of …

[HTML][HTML] Leveraging digital media data for pharmacovigilance

H Farooq, JS Niaz, S Fakhar… - AMIA Annual Symposium …, 2020 - ncbi.nlm.nih.gov
The development of novel drugs in response to changing clinical requirements is a complex
and costly method with uncertain outcomes. Postmarket pharmacovigilance is essential as …

Arteriovenous fistula maturation and the influence of fluid dynamics

E Colley, A Simmons, R Varcoe… - Proceedings of the …, 2020 - journals.sagepub.com
Arteriovenous fistula creation is the preferred vascular access for haemodialysis therapy,
but has a large failure rate in the maturation period. This period generally lasts 6 to 8 weeks …

[BOOK][B] Chronic Neurovascular Dysfunction in a Preclinical Model of Repeated Mild Traumatic Brain Injury

C Adams - 2018 - search.proquest.com
Outcomes associated with repeated mild traumatic brain injury (mTBI) are considerably worse
than those of a single mTBI. Despite higher prevalence relative to moderate injuries, the …

Manifold-aware Forests: Closing the Gap to Convolutional Neural Networks

R Perry, F LINDEBERG - 2020 - jscholarship.library.jhu.edu
Decision forests (DF), in particular random forests and gradient boosting trees, have
demonstrated state-of-the-art accuracy compared to other methods in many supervised learning …

[BOOK][B] The effect of computer-aided lab instruction on achievement in fundamentals of college algebra

SE Easterling - 1991 - search.proquest.com
The purpose of this study was to determine whether a computer-based mandatory lab for
Fundamentals of College Algebra produces higher academic performance than a traditional …

[BOOK][B] The Recorder Idiom In The Instrumental Music Of Georg Philipp Telemann.

TR Mosser - 1975 - search.proquest.com
430 VITA.............................. 433 iv LIST OF TABLES Table I. Common Fingerings for Various
Sizes of Recorders.... 40 II. Fingerings Common to the Flute and Various Recorders.. 57 III. …